(Q58844735)

English

Monocyte-derived dendritic cells from chagasic patients vs healthy donors secrete differential levels of IL-10 and IL-12 when stimulated with a protein fragment of Trypanosoma cruzi heat-shock protein-70

scientific article published on 8 January 2008

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scholarly article

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Monocyte-derived dendritic cells from chagasic patients vs healthy donors secrete differential levels of IL-10 and IL-12 when stimulated with a protein fragment of Trypanosoma cruzi heat-shock protein-70 (English)

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Trypanosoma cruzi

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inferred from title

Manuel Carlos López

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author name string

Adriana Cuellar

1

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Sandra Paola Santander

2

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María Del Carmen Thomas

3

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Fanny Guzmán

4

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Alberto Gómez

5

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Manuel Carlos López

6

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Concepción J Puerta

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María del Carmen Thomas

3

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language of work or name

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publication date

8 January 2008

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Immunology & Cell Biology

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86

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3

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255-60

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255-260

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Chagas disease: current epidemiological trends after the interruption of vectorial and transfusional transmission in the Southern Cone countries

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Chagas' disease

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Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

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Molecular Comparison of the Mitochondrial and Cytoplasmic hsp 70 of Trypanosoma cruzi, Trypanosoma brucei and Leishmania major

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Cytoplasmic-nuclear translocation of the Hsp70 protein during environmental stress in Trypanosoma cruzi

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Human antibody responses to Trypanosoma cruzi 70-kD heat-shock proteins

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Prevalence of antibodies against Trypanosoma cruzi in blood bank donors from the IMSS General Hospital in Orizaba, Veracruz, Mexico

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HSP70 from Trypanosoma cruzi is endowed with specific cell proliferation potential leading to apoptosis

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Trypanosoma cruzi heat-shock protein-70 kDa,alone or fused to the parasite KMP11 antigen, induces functional maturation of murine dendritic cells

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Immunostimulatory properties of the Leishmania infantum heat shock proteins HSP70 and HSP83

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The immunization of A2/K(b) transgenic mice with the KMP11-HSP70 fusion protein induces CTL response against human cells expressing the T. cruzi KMP11 antigen: identification of A2-restricted epitopes

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The genetic immunization with paraflagellar rod protein-2 fused to the HSP70 confers protection against late Trypanosoma cruzi infection

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DNA immunization with Trypanosoma cruzi HSP70 fused to the KMP11 protein elicits a cytotoxic and humoral immune response against the antigen and leads to protection.

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Expresión de marcadores en células dendríticas de pacientes chagásicos crónicos estimuladas con la proteína KMP-11 y el péptido K1 de Trypanosoma cruzi

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CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin

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Roles of heat-shock proteins in innate and adaptive immunity

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Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells.

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Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells.

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Breaking the non-responsiveness of C57BL/6 mice to the malarial antigen EB200--the role of carrier and adjuvant molecules

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Enhancement of DNA vaccine potency by linkage of Plasmodium falciparum malarial antigen gene fused with a fragment of HSP70 gene

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Microbial heat shock protein 70 stimulatory properties have different TLR requirements

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Trypanosoma cruzi infects human dendritic cells and prevents their maturation: inhibition of cytokines, HLA-DR, and costimulatory molecules.

1 reference

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Trypanosoma cruzi down-regulates lipopolysaccharide-induced MHC class I on human dendritic cells and impairs antigen presentation to specific CD8(+) T lymphocytes.

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In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4(+) T cell independent

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The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors

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Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype.

1 reference

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CD91: a receptor for heat shock protein gp96

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Toxoplasma gondii-derived heat shock protein 70 stimulates maturation of murine bone marrow-derived dendritic cells via Toll-like receptor 4.

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Mycobacterium avium ssp. paratuberculosis recombinant heat shock protein 70 interaction with different bovine antigen-presenting cells

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Identification of stimulating and inhibitory epitopes within the heat shock protein 70 molecule that modulate cytokine production and maturation of dendritic cells.

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Endotoxin-free heat-shock protein 70 fails to induce APC activation

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The two faces of interleukin 10 in human infectious diseases

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IL-12 and IL-23: master regulators of innate and adaptive immunity.

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Kinetics of antigen-induced phenotypic and functional maturation of human monocyte-derived dendritic cells.

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Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection

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Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin

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Chronic exposure to Helicobacter pylori impairs dendritic cell function and inhibits Th1 development

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A postmigrational switch among skin-derived dendritic cells to a macrophage-like phenotype is predetermined by the intracutaneous cytokine balance.

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Synthesis, isolation and characterization of Plasmodium falciparum antigenic tetrabranched peptide dendrimers obtained by thiazolidine linkages

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10.1038/SJ.ICB.7100146

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