(Q58853213)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995012%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Amifostine (WR-2721) selective protection against melphalan genotoxicity (English)

1 reference

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10 November 2019

0 references

0 references

1 reference

1

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10 November 2019

Carmelo Carlo-Stella

3

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10 November 2019

author name string

E Anceschi

2

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10 November 2019

E Regazzi

4

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10 November 2019

V Rizzoli

5

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10 November 2019

P Poli

6

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10 November 2019

C Rossi

7

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10 November 2019

publication date

1 September 2000

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10 November 2019

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10 November 2019

volume

14

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10 November 2019

issue

9

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10 November 2019

page(s)

1642-1651

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2401877

10 November 2019

exact match

0 references

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Concentration-dependent protection against X-ray-induced chromosome aberrations in human lymphocytes by the aminothiol WR-1065

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Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells

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7 January 2021

Biochemical modification of the toxicity and the anti-tumour effect of 5-fluorouracil and cis-platinum by WR-2721 in mice

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7 January 2021

Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained

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7 January 2021

In vitro effect of amifostine on haematopoietic progenitors exposed to carboplatin and non-alkylating antineoplastic drugs: haematoprotection acts as a drug-specific progenitor rescue

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7 January 2021

The modification of melphalan toxicity in tumor bearing mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (WR2721)

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7 January 2021

Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721

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7 January 2021

DNA adenine adducts induced by nitrogen mustards and their role in transcription termination in vitro.

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7 January 2021

Detection of DNA damage induced by human carcinogens in acellular assays: potential application for determining genotoxic mechanisms

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7 January 2021

Specificity and kinetics of interstrand and intrastrand bifunctional alkylation by nitrogen mustards at a G-G-C sequence

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7 January 2021

Mutagenic damage to mammalian cells by therapeutic alkylating agents

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7 January 2021

Melphalan, a second chemical for which specific-locus mutation induction in the mouse is maximum in early spermatids

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7 January 2021

Dominant lethal and heritable translocation tests with chlorambucil and melphalan in male mice

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7 January 2021

Influence of WR 2721 on the efficacy of radiotherapy and chemotherapy of murine tumors

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7 January 2021

Effect of the radioprotector WR 2721 on the response of metastatic Lewis lung carcinoma colonies to alkylating agents

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7 January 2021

A simple technique for quantitation of low levels of DNA damage in individual cells

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7 January 2021

The comet assay: a comprehensive review

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7 January 2021

The alkaline single cell gel electrophoresis assay with mouse multiple organs: results with 30 aromatic amines evaluated by the IARC and U.S. NTP.

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7 January 2021

EVALUATION OF THREE METHODS FOR THE DETECTION OF DNA SINGLE-STRAND BREAKS IN HUMAN LYMPHOCYTES: ALKALINE ELUTION, NICK TRANSLATION, AND SINGLE-CELL GEL ELECTROPHORESIS

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7 January 2021

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7 January 2021

Use of the comet test in the evaluation of multidrug resistance of human cell lines

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7 January 2021

Early detection of staurosporine-induced apoptosis by comet and annexin V assays.

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7 January 2021

Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells

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7 January 2021

Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single-cell electrophoresis.

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7 January 2021

Calibration of the single cell gel electrophoresis assay, flow cytometry analysis and forward mutation in Chinese hamster ovary cells

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7 January 2021

Comet assay and DNA flow cytometry analysis of staurosporine-induced apoptosis

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7 January 2021

Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay

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7 January 2021

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7 January 2021

Evaluation of DNA damage in leukocytes of ex-smokers by single cell gel electrophoresis

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7 January 2021

Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt–tungsten carbide

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7 January 2021

Determination of radiation-induced damage in lymphocytes using the micronucleus and microgel electrophoresis 'Comet' assays

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7 January 2021

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7 January 2021

Detection of MNNG-induced DNA lesions in mammalian cells; validation of comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations.

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7 January 2021

Correlations between DNA and cytogenetic damage induced after chemical treatment and radiation

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7 January 2021

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7 January 2021

Detection of DNA lesions induced by chemical mutagens by the single cell electrophoresis (Comet) assay. 1. Relationship between the onset of DNA damage and the characteristics of mutagens

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7 January 2021

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7 January 2021

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7 January 2021

Evaluation of the genotoxic activity of paclitaxel by the in vitro micronucleus test in combination with fluorescent in situ hybridization of a DNA centromeric probe and the alkaline single cell gel electrophoresis technique (comet assay) in human T

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7 January 2021

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7 January 2021

Human cDNA-expressed cytochrome P450 IA2: mutagen activation and substrate specificity

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7 January 2021

The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives

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7 January 2021

Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Detection of subpopulations resistant to DNA-damaging agents in spheroids and murine tumours

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7 January 2021

Analysis of DNA oxidative damage related to cell proliferation

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7 January 2021

Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay

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7 January 2021

Exercise-induced DNA effects in human leukocytes are not accompanied by increased formation of 8-hydroxy-2'-deoxyguanosine or induction of micronuclei

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2401877

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995012%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference