(Q59285788)

English

Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2)

scientific article published on 01 April 1997

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2) (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Patrick F Augustijns

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

R Kinget

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

E de Clercq

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

publication date

1 April 1997

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

14

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

492-496

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Oral, subcutaneous, and intramuscular bioavailabilities of the antiviral nucleotide analog 9-(2-phosphonylmethoxyethyl) adenine in cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, oral bioavailability determination, and in vitro evaluation of prodrugs of the antiviral agent 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

9-(2-Phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and antitumor evaluation of bis[(pivaloyloxy)methyl] 2'-deoxy-5-fluorouridine 5'-monophosphate (FdUMP): a strategy to introduce nucleotides into cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and in vitro antiretroviral activities of bis(pivaloyloxymethyl) prodrugs of acyclic nucleoside phosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral bioavailability of the antiretroviral agent 9-(2-phosphonylmethoxyethyl)adenine (PMEA) from three formulations of the prodrug bis(pivaloyloxymethyl)-PMEA in fasted male cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/9144737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1012155717819

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9144737%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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