(Q59300350)

English

Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-α in patients with metastatic melanoma: a randomised "proof-of-principle" phase II

scientific article published on 22 July 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053129%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-α in patients with metastatic melanoma: a randomised "proof-of-principle" phase II study (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053129%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

metastatic melanoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

6

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10 March 2020

Laura Fiammenghi

8

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10 March 2020

Massimo Guidoboni

18

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10 March 2020

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Francesco de Rosa

1

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10 March 2020

Laura Ridolfi

2

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10 March 2020

Ruggero Ridolfi

3

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10 March 2020

Giorgia Gentili

4

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10 March 2020

Linda Valmorri

5

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10 March 2020

Massimiliano Petrini

7

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10 March 2020

Anna Maria Granato

9

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10 March 2020

Valentina Ancarani

10

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10 March 2020

Elena Pancisi

11

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10 March 2020

Valentina Soldati

12

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10 March 2020

Serena Cassan

13

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10 March 2020

Angela Riccobon

14

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10 March 2020

Elisabetta Parisi

15

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10 March 2020

Antonino Romeo

16

1 reference

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10 March 2020

Livia Turci

17

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10 March 2020

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22 July 2014

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10 March 2020

Journal of Translational Medicine

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10 March 2020

12

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10 March 2020

1

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209

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Europe PubMed Central

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10 March 2020

https://scigraph.springernature.com/pub.10.1186/1479-5876-12-209

0 references

The roles of IFN gamma in protection against tumor development and cancer immunoediting

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer immunoediting: from immunosurveillance to tumor escape

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early selection in a randomized phase II clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune modulation by ionizing radiation and its implications for cancer immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of ionizing radiation-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural innate and adaptive immunity to cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutaneous melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiotherapy effects on anti-tumor immunity: implications for cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic effects of local radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor endothelial marker 8 expression levels in dendritic cell-based cancer vaccines are related to clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunologic correlates of the abscopal effect in a patient with melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A clinical development paradigm for cancer vaccines and related biologics

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomonitoring Tumor-Specific T Cells in Delayed-Type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates With Clinical Outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the expression of the interleukin-1 beta gene in mouse spleen by ionizing radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unexpected high response rate to traditional therapy after dendritic cell-based vaccine in advanced melanoma: update of clinical outcome and subgroup analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells in cancer immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cell-based vaccine in advanced melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionizing radiation modulates the exposure of the HUIV26 cryptic epitope within collagen type IV during angiogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The COSTIM bioassay: a novel potency test for dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved endpoints for cancer immunotherapy trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4+CD25++Foxp3+ regulatory T-cells in advanced melanoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effects of type I interferons on cells of the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging toxicity profiles of anti-CTLA-4 antibodies across clinical indications

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of in vivo labelled dendritic cell migration in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trial designs for therapeutic cancer vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemic cell products down-regulate human dendritic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concomitant detection of IFNα signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNα-treated subjects at early times after repeated local cytokine treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of tumour endothelial marker-8 by interleukin-1beta and its impact in IL-1beta induced angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining radiotherapy and cancer immunotherapy: a paradigm shift

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trial designs for evaluating the medical utility of prognostic and predictive biomarkers in oncology

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FRET microscopy autologous tumor lysate processing in mature dendritic cell vaccine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistological analysis of peptide-induced delayed-type hypersensitivity in advanced melanoma patients treated with melanoma antigen-pulsed mature monocyte-derived dendritic cell vaccination

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25053129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1479-5876-12-209

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053129%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053129%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053129%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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