(Q59326990)

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A systematic review of the validity of patient derived xenograft (PDX) models: the implications for translational research and personalised medicine

scientific article published on 21 November 2018

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scholarly article

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A systematic review of the validity of patient derived xenograft (PDX) models: the implications for translational research and personalised medicine (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

1 reference

based on heuristic

inferred from title

systematic review

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based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

author name string

Anne T. Collins

1

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Shona H. Lang

2

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publication date

21 November 2018

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

e5981

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

copyright license

Creative Commons Attribution 4.0 International

21 November 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Growth of human digestive-tumour xenografts in athymic nude rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenografts of primary human prostatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent development of murine T-cell lymphomas with TcR alpha/beta+, CD4-/8- phenotype after implantation of human inflammatory breast cancer cells in BALB/c nude mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment and characterization of in vivo human tumor models in the NOD/SCID/gamma(c)(null) mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From human to mouse and back: 'tumorgraft' models surge in popularity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment and genomic characterization of mouse xenografts of human primary prostate tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human prostate cancer heterotransplants: a review on this experimental model

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Finding the tumor copycat. Therapy fails, patients don't

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brief report: a bioassay to identify primary human prostate cancer repopulating cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of a novel VEGF targeted agent using patient-derived tumor tissue xenograft models of colon carcinoma with lymphatic and hepatic metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal evolution in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-derived tumour xenografts as models for oncology drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Lymphomas Developing in Immunodeficient Mice Implanted With Primary Human Non–Small Cell Lung Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human solid tumor xenografts in immunodeficient mice are vulnerable to lymphomagenesis associated with Epstein-Barr virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociated primary human prostate cancer cells coinjected with the immortalized Hs5 bone marrow stromal cells generate undifferentiated tumors in NOD/SCID-γ mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-derived tumor xenografts: transforming clinical samples into mouse models

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour heterogeneity and cancer cell plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour heterogeneity in the clinic

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SYRCLE's risk of bias tool for animal studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel animal model for locally advanced breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Setting up a wide panel of patient-derived tumor xenografts of non-small cell lung cancer by improving the preanalytical steps

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early development of human lymphomas in a prostate cancer xenograft program using triple knock-out immunocompromised mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new mouse avatar model of non-small cell lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extent of inflammatory infiltration in primary cancer tissues is associated with lymphomagenesis in immunodeficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initiation and characterization of small cell lung cancer patient-derived xenografts from ultrasound-guided transbronchial needle aspirates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-Derived Tumor Xenografts Are Susceptible to Formation of Human Lymphocytic Tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An original patient-derived xenograft of prostate cancer with cyst formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the risk of lymphomagenesis in xenografts by the PCR-based detection of EBV BamHI W region in patient cancer specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rayyan-a web and mobile app for systematic reviews.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of patient-derived xenografts from fine needle aspirates or core needle biopsy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin Inhibits Cellular Proliferation and Bioenergetics in Colorectal Cancer Patient-Derived Xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systematic review of the asymmetric inheritance of cellular organelles in eukaryotes: A critique of basic science validity and imprecision.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program

1 reference

https://pubmed.ncbi.nlm.nih.gov/30498642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.7717/PEERJ.5981

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30498642%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

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