(Q59348641)

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Rapid regulation of collagen but not metalloproteinase 1, 3, 13, 14 and tissue inhibitor of metalloproteinase 1, 2, 3 expression in response to mechanical loading of cartilage explants in vitro

scientific article published on 01 February 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12559975%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

Rapid regulation of collagen but not metalloproteinase 1, 3, 13, 14 and tissue inhibitor of metalloproteinase 1, 2, 3 expression in response to mechanical loading of cartilage explants in vitro (English)

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17 December 2019

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17 December 2019

Wiltrud Richter

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17 December 2019

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Andreas Fehrenbacher

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17 December 2019

Eric Steck

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17 December 2019

Wolfgang Roth

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17 December 2019

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1 February 2003

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17 December 2019

Archives of Biochemistry and Biophysics

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17 December 2019

410

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17 December 2019

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17 December 2019

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17 December 2019

The extracellular matrix, interstitial fluid and ions as a mechanical signal transducer in articular cartilage

1 reference

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Mechanotransduction via integrins and interleukinâ 4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes

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Load-controlled compression of articular cartilage induces a transient stimulation of aggrecan gene expression

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Compression of cartilage results in differential effects on biosynthetic pathways for aggrecan, link protein, and hyaluronan

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Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1.

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Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis

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Cartilage viability after repetitive loading: a preliminary report

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Human chondrocyte apoptosis in response to mechanical injury

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Chondrocyte necrosis and apoptosis in impact damaged articular cartilage

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7 January 2021

Biosynthetic response and mechanical properties of articular cartilage after injurious compression

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7 January 2021

Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow

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7 January 2021

Biosynthetic response of cartilage explants to dynamic compression

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7 January 2021

Mechanical regulation of cartilage biosynthetic behavior: physical stimuli

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7 January 2021

Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in vitro

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7 January 2021

An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide

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7 January 2021

Regulation of extracellular matrix gene expression by mechanical stress

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7 January 2021

Cartilage tissue remodeling in response to mechanical forces

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7 January 2021

In situ measurement of articular cartilage deformation in intact femoropatellar joints under static loading

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7 January 2021

Deformation of loaded articular cartilage prepared for scanning electron microscopy with rapid freezing and freeze-substitution fixation

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7 January 2021

The extent of matrix damage and chondrocyte death in mechanically traumatized articular cartilage explants depends on rate of loading

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7 January 2021

Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent

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7 January 2021

Effects of intermittently applied cyclic loading on proteoglycan metabolism and swelling behaviour of articular cartilage explants

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7 January 2021

Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration

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7 January 2021

Effects of static and cyclic compressive loading on articular cartilage plugs in vitro

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Effect of methylprednisolone and mechanical loading on canine articular cartilage in explant culture

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7 January 2021

Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro

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7 January 2021

Characterization of cartilage metabolic response to static and dynamic stress using a mechanical explant test system

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7 January 2021

Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.

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7 January 2021

The regulation of MMPs and TIMPs in cartilage turnover

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7 January 2021

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

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Collagen fibre arrangement in the tibial plateau articular cartilage of man and other mammalian species

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Insulin-like growth factor-1 and transforming growth factor-beta1 accelerates osteotomy healing using polylactide-coated implants as a delivery system: a biomechanical and histological study in minipigs

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Functional anatomy of articular cartilage under compressive loading Quantitative aspects of global, local and zonal reactions of the collagenous network with respect to the surface integrity

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Basic FGF mediates an immediate response of articular cartilage to mechanical injury

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Chondrogenesis in cartilage repair is induced by members of the transforming growth factor-beta superfamily

1 reference

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based on heuristic

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Identifiers

10.1016/S0003-9861(02)00658-6

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12559975%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12559975%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

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