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Lipid-based vehicles for the oral delivery of poorly water soluble drugs
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scholarly article
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title
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
(English)
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author name string
Andrew J. Humberstone
series ordinal
1
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William N. Charman
series ordinal
2
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language of work or name
English
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publication date
April 1997
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published in
Advanced Drug Delivery Reviews
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volume
25
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issue
1
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page(s)
103-128
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cites work
Intestinal synthesis, secretion, and transport of lipoproteins
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Intestinal aspects of lipid absorption: in review
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Lipid Digestion and Absorption
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Fat digestion in the newborn. Characterization of lipase in gastric aspirates of premature and term infants
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Fat digestion by lingual lipase: mechanism of lipolysis in the stomach and upper small intestine
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Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase
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The characteristics of mixed micellar solutions with particular reference to bile
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Micelle formation by bile salts. Physical-chemical and thermodynamic considerations
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Solubilization and wetting effects of bile salts on the dissolution of steroids
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Comparison of the mechanism of dissolution of hydrocortisone in simple and mixed micelle systems
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THE INTRALUMINAL PHASE OF FAT DIGESTION IN MAN: THE LIPID CONTENT OF THE MICELLAR AND OIL PHASES OF INTESTINAL CONTENT OBTAINED DURING FAT DIGESTION AND ABSORPTION
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Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings
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Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings
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The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell
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The relationship between uptake in vitro of oleic acid and micellar solubilization
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Mechanism of intestinal fatty acid uptake in the rat: the role of an acidic microclimate
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Partitioning of polar fatty acids into lymph and portal vein after intestinal absorption in the rat.
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A relation between the chain length of fatty acids and the slowing of gastric emptying
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Mechanisms of Surfactant Effects on Drug Absorption
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Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route
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Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation or presystemic metabolism
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Bioavailability of phenytoin in lipid containing dosage forms in rats
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Comparative bioavailability of a lipophilic steroid
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Low-melting phenytoin prodrugs as alternative oral delivery modes for phenytoin: a model for other high-melting sparingly water-soluble drugs
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Enhancement of the oral bioavailability of cinnarizine in oleic acid in beagle dogs
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Biopharmaceutics of Drugs Administered in Lipid-Containing Dosage Forms I: GI Absorption of Griseofulvin from an Oil-in-Water Emulsion in the Rat
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Effects of lipids on bioavailability of sulfisoxazole acetyl, dicumarol, and griseofulvin in rats
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Effect of Various Vehicles and Vehicle Volumes on Oral Absorption of Triamterene in Rats
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Bioavailability of Micronized Griseofulvin from Corn Oil‐in‐Water Emulsion, Aqueous Suspension, and Commercial Tablet Dosage Forms in Humans
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The role of calcium ions and bile salts on the pancreatic lipase-catalyzed hydrolysis of triglyceride emulsions stabilized with lecithin
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1 reference
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7 January 2021
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1 reference
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1 reference
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1 reference
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7 January 2021
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inferred from DOI database lookup
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1 reference
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https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cyclosporine bioavailability from a microemulsion formulation in a liver transplant recipient
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Absorption of cyclosporin from conventional and new microemulsion oral formulations in liver transplant recipients with external biliary diversion
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of food and a monoglyceride emulsion formulation on danazol bioavailability
1 reference
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https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of food on the pharmacokinetics of cyclosporine in healthy subjects following oral and intravenous administration
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects
1 reference
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7 January 2021
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inferred from DOI database lookup
Phase studies of mixed phosphated surfactants, n-hexane and water
1 reference
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https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
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inferred from DOI database lookup
Measurement of the 'spontaneity' of self-emulsifiable oils
1 reference
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https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
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Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solid dispersion of morphine-tristearin with reduced presystemic inactivation in rats
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increasing intestinal absorption of drugs by formulation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristics of drug-phospholipid coprecipitates I: Physical properties and dissolution behavior of griseofulvin-dimyristoylphosphatidylcholine systems
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristics of drug-phospholipid coprecipitates. II: Bioavailability studies of griseofulvin in rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oral bioavailability of griseofulvin from aged griseofulvin:lipid coprecipitates: in vivo studies in rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of Vehicle Amphiphilicity on the Dissolution and Bioavailability of a Poorly Water-Soluble Drug from Solid Dispersions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bioavailability of a poorly water-soluble drug from tablet and solid dispersion in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of the oral absorption of cyclosporin in man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
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inferred from DOI database lookup
The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system
1 reference
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https://api.crossref.org/works/10.1016%2FS0169-409X%2896%2900494-2
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7 January 2021
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10.1016/S0169-409X(96)00494-2
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