(Q59632286)

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Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma

scientific article published on 24 April 2008

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7 January 2020

Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma (English)

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7 January 2020

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7 January 2020

Kingston H Mills

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7 January 2020

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Deirdre Toomey

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7 January 2020

Caroline Sutton

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7 January 2020

Andrew G Jarnicki

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7 January 2020

Sarah C Higgins

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24 April 2008

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7 January 2020

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7 January 2020

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7 January 2020

27-28

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7 January 2020

3540-3549

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7 January 2020

Cancer immunotherapy: moving beyond current vaccines

1 reference

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7 January 2021

Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world

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7 January 2021

Therapeutic cancer vaccines

1 reference

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Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells

1 reference

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7 January 2021

CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes

1 reference

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7 January 2021

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

1 reference

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Stimulation of Th1-polarizing cytokines, C-C chemokines, maturation of dendritic cells, and adjuvant function by the peptide binding fragment of heat shock protein 70.

1 reference

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7 January 2021

Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations

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7 January 2021

Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity

1 reference

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7 January 2021

CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin

1 reference

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7 January 2021

Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells

1 reference

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7 January 2021

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

1 reference

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7 January 2021

Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype.

1 reference

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7 January 2021

Cellular requirements for tumor-specific immunity elicited by heat shock proteins: tumor rejection antigen gp96 primes CD8+ T cells in vivo

1 reference

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7 January 2021

Imiquimod: mode of action

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Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: a success story with room for improvement.

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Inflammation and cancer

1 reference

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7 January 2021

Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells

1 reference

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7 January 2021

Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer

1 reference

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7 January 2021

CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition

1 reference

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7 January 2021

Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO.

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7 January 2021

Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming

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7 January 2021

Dendritic cells in antitumor immune responses. I. Defective antigen presentation in tumor-bearing hosts

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7 January 2021

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.

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7 January 2021

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

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7 January 2021

Dendritic cells in cancer immunotherapy

1 reference

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7 January 2021

Dendritic cell-based tumor vaccines and antigen presentation attenuators

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7 January 2021

Dendritic cells produce eicosanoids, which modulate generation and functions of antigen-presenting cells

1 reference

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7 January 2021

Autoregulation of human monocyte-derived dendritic cell maturation and IL-12 production by cyclooxygenase-2-mediated prostanoid production

1 reference

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7 January 2021

Prostaglandin E2 promotes the survival of bone marrow-derived dendritic cells

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7 January 2021

Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography

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7 January 2021

Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow

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Therapeutic response of basal cell carcinoma to the immune response modifier imiquimod 5% cream

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In vivo manipulation of dendritic cells overcomes tolerance to unmodified tumor-associated self antigens and induces potent antitumor immunity.

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Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.

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TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours

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The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors

1 reference

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7 January 2021

Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells

1 reference

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Optimizing dendritic cell-based anticancer immunotherapy: maturation state does have clinical impact

1 reference

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Prostaglandin E2 exacerbates collagen-induced arthritis in mice through the inflammatory interleukin-23/interleukin-17 axis

1 reference

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7 January 2021

Identifiers

10.1016/J.VACCINE.2008.04.005

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479787%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479787%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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