(Q60046359)

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15 April 2020

title

Role of indoleamine 2,3-dioxygenase in pathology of the gastrointestinal tract (English)

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15 April 2020

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1

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15 April 2020

Crissy Fellabaum

5

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15 April 2020

author name string

Marina Gazdic

2

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15 April 2020

Nemanja Jovicic

3

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15 April 2020

Nebojsa Arsenijevic

6

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15 April 2020

Vladislav Volarevic

7

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15 April 2020

C Randall Harrell

4

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15 April 2020

publication date

6 December 2018

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Therapeutic Advances in Gastroenterology

15 April 2020

published in

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15 April 2020

volume

11

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15 April 2020

page(s)

1756284818815334

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Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase

15 April 2020

cites work

1 reference

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Induction of pulmonary indoleamine 2,3-dioxygenase by interferon

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12 December 2020

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

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Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes

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Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites

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T cell apoptosis by tryptophan catabolism

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The three Es of cancer immunoediting

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Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease

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Study of indoleamine 2,3-dioxygenase expression in patients of esophageal squamous cell carcinoma

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The Jak-STAT pathway stimulated by interferon gamma.

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Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.

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Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

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12 December 2020

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

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12 December 2020

Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.

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Dysfunction of CD4+CD25high T regulatory cells in patients with recurrent aphthous stomatitis.

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Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis

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Inflamed intestinal mucosa features a specific epithelial expression pattern of indoleamine 2,3-dioxygenase

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

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SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis

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A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA.

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Indoleamine 2,3-dioxygenase expression and regulation in chronic periodontitis

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Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

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12 December 2020

Anti-CTLA-4 treatment induces IL-10-producing ICOS+ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitis

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12 December 2020

Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function

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12 December 2020

Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis

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12 December 2020

Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis

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12 December 2020

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.

1 reference

12 December 2020

Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion

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12 December 2020

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

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12 December 2020

The role of interleukin-17 in the Helicobacter pylori induced infection and immunity

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12 December 2020

Expression and prognostic impact of indoleamine 2,3-dioxygenase in oral squamous cell carcinomas.

1 reference

12 December 2020

Immunoactivative role of indoleamine 2,3‑dioxygenase in gastric cancer cells in vitro

1 reference

12 December 2020

Myeloid CD11c+ S100+ dendritic cells express indoleamine 2,3-dioxygenase at the inflammatory border to invasive lower lip squamous cell carcinoma

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12 December 2020

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

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12 December 2020

Amelioration of 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice by immunoregulatory dendritic cells.

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12 December 2020

Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation

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12 December 2020

Kynurenine pathway metabolites in humans: disease and healthy States

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12 December 2020

Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase

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12 December 2020

Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase.

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12 December 2020

Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease

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12 December 2020

Indoleamine 2,3-dioxygenase: from catalyst to signaling function

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12 December 2020

Tryptophan depletion and the kinase GCN2 mediate IFN-γ-induced autophagy.

1 reference

12 December 2020

The role of tryptophan side chains in membrane protein anchoring and hydrophobic mismatch.

1 reference

12 December 2020

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

1 reference

12 December 2020

Lipopolysaccharide-induced indoleamine 2,3-dioxygenase expression in the periodontal ligament.

1 reference

12 December 2020

Therapeutic gene modified cell based cancer vaccines

1 reference

12 December 2020

Mesenchymal stem cells from periapical lesions modulate differentiation and functional properties of monocyte-derived dendritic cells.

1 reference

12 December 2020

IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice

1 reference

12 December 2020

IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.

1 reference

12 December 2020

The correlation between the subsets of tumor infiltrating memory T cells and the expression of indoleamine 2,3-dioxygenase in gastric cancer

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase: expressing cells in inflammatory bowel disease-a cross-sectional study.

1 reference

12 December 2020

A tryptophan metabolite, kynurenine, promotes mast cell activation through aryl hydrocarbon receptor

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12 December 2020

The role of plasma IDO activity as a diagnostic marker of patients with colorectal cancer

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer

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12 December 2020

The subsets of dendritic cells and memory T cells correspond to indoleamine 2,3-dioxygenase in stomach tumor microenvironment.

1 reference

12 December 2020

Minireview: Gut microbiota: the neglected endocrine organ

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12 December 2020

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

1 reference

12 December 2020

The targeting of indoleamine 2,3 dioxygenase -mediated immune escape in cancer

1 reference

12 December 2020

Enhanced expression of indoleamine 2,3-dioxygenase in Helicobacter pylori-infected human gastric mucosa modulates Th1/Th2 pathway and interleukin 17 production

1 reference

12 December 2020

Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model

1 reference

12 December 2020

A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors

1 reference

12 December 2020

AhR-Mediated, Non-Genomic Modulation of IDO1 Function

1 reference

12 December 2020

Low expression of Bin1, along with high expression of IDO in tumor tissue and draining lymph nodes, are predictors of poor prognosis for esophageal squamous cell cancer patients

1 reference

12 December 2020

Tryptophan-degrading enzymes in tumoral immune resistance

1 reference

12 December 2020

Trial watch: IDO inhibitors in cancer therapy

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12 December 2020

Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase (IDO): Biology and Target in Cancer Immunotherapies

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12 December 2020

Promises and paradoxes of regulatory T cells in inflammatory bowel disease

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12 December 2020

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

1 reference

12 December 2020

Tryptophan Biochemistry: Structural, Nutritional, Metabolic, and Medical Aspects in Humans

1 reference

12 December 2020

Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma

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12 December 2020

The expression and prognostic relevance of indoleamine 2,3-dioxygenase in tongue squamous cell carcinoma.

1 reference

12 December 2020

DPSCs from Inflamed Pulp Modulate Macrophage Function via the TNF-α/IDO Axis

1 reference

12 December 2020

The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets.

1 reference

12 December 2020

Induction of Indoleamine 2,3-dioxygenase by Pre-treatment with Poly(I:C) May Enhance the Efficacy of MSC Treatment in DSS-induced Colitis

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12 December 2020

First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies.

1 reference

12 December 2020

Interleukin-4 Inhibits Regulatory T Cell Differentiation through Regulating CD103+ Dendritic Cells

1 reference

12 December 2020

The rationale of indoleamine 2,3-dioxygenase inhibition for cancer therapy.

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase and regulatory t cells in intestinal mucosa in children with inflammatory bowel disease.

1 reference

12 December 2020

Tumor-Associated Fibroblasts and Microvessels Contribute to the Expression of Immunosuppressive Factor Indoleamine 2, 3-Dioxygenase in Human Esophageal Cancers.

1 reference

12 December 2020

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

1 reference

12 December 2020

Functional heterogeneity of gut-resident regulatory T cells

1 reference

12 December 2020

Molecular and Cellular Mechanisms Involved in Mesenchymal Stem Cell-Based Therapy of Inflammatory Bowel Diseases.

1 reference

12 December 2020

Fecal Calprotectin: A Reliable Predictor of Mucosal Healing after Treatment for Active Ulcerative Colitis

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12 December 2020

Bifidobacteria alleviate experimentally induced colitis by upregulating indoleamine 2, 3-dioxygenase expression

1 reference

12 December 2020

Surrogate Fecal Biomarkers in Inflammatory Bowel Disease: Rivals or Complementary Tools of Fecal Calprotectin?

1 reference

12 December 2020

Tryptophan Catabolism and Cancer Immunotherapy Targeting IDO Mediated Immune Suppression

1 reference

12 December 2020

The Role of Indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy

1 reference

12 December 2020

Intraperitoneal administration of mesenchymal stem cells ameliorates acute dextran sulfate sodium-induced colitis by suppressing dendritic cells.

1 reference

12 December 2020

1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells.

1 reference

12 December 2020

The Impact of Indoleamine 2,3-dioxygenase (IDO) Expression on Stage III Gastric Cancer

1 reference

12 December 2020

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

1 reference

12 December 2020

Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors.

1 reference

12 December 2020

The role of T helper 1-cell response in Helicobacter pylori-infection

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase-dependent expansion of T-regulatory cells maintains mucosal healing in ulcerative colitis

1 reference

12 December 2020

Identifiers

DOI

10.1177/1756284818815334

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30574192%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30574192%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

30574192

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