(Q60178445)

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KSHV LANA1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA binding, replication, and episome persistence

scientific article published on 01 February 2004

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24 November 2019

KSHV LANA1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA binding, replication, and episome persistence (English)

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Europe PubMed Central

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24 November 2019

Mary E Ballestas

2

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24 November 2019

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Takashi Komatsu

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24 November 2019

Andrew J Barbera

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24 November 2019

Brenna Kelley-Clarke

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24 November 2019

Kenneth M Kaye

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24 November 2019

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1 February 2004

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24 November 2019

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24 November 2019

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24 November 2019

225-236

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24 November 2019

Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells

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Mechanistic studies on the DNA linking activity of Epstein-Barr nuclear antigen 1.

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Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA.

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Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

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7 January 2021

Interaction of the papillomavirus E2 protein with mitotic chromosomes

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Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA 1

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7 January 2021

Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein, EBNA1, bound to DNA.

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

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Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein-Barr virus

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The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells

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7 January 2021

The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen binds to specific sequences at the left end of the viral genome through its carboxy-terminus

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7 January 2021

The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients.

1 reference

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7 January 2021

Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin

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7 January 2021

CAFASP-1: Critical assessment of fully automated structure prediction methods

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7 January 2021

Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus

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7 January 2021

The Epstein-Barr virus origin of plasmid replication, oriP, contains both the initiation and termination sites of DNA replication

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7 January 2021

Molecular polymorphism of Kaposi's sarcoma-associated herpesvirus (Human herpesvirus 8) latent nuclear antigen: evidence for a large repertoire of viral genotypes and dual infection with different viral genotypes.

1 reference

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7 January 2021

DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus

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7 January 2021

Latency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication

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7 January 2021

The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein

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7 January 2021

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids.

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7 January 2021

Ultraspiracle, a Drosophila retinoic X receptor alpha homologue, can mobilize the human thyroid hormone receptor to transactivate a human promoter.

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7 January 2021

Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa

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7 January 2021

Selective extraction of polyoma DNA from infected mouse cell cultures

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7 January 2021

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells

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7 January 2021

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus

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7 January 2021

Enhanced genome annotation using structural profiles in the program 3D-PSSM

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7 January 2021

Identification of Epstein-Barr virus nuclear antigen 1 protein domains that direct interactions at a distance between DNA-bound proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation

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7 January 2021

Functional dissection of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus involved in latent DNA replication and transcription of terminal repeats of the viral genome.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

Studies on the mechanism of DNA linking by Epstein-Barr virus nuclear antigen 1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection

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7 January 2021

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

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7 January 2021

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

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Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus

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Carboxy terminus of human herpesvirus 8 latency-associated nuclear antigen mediates dimerization, transcriptional repression, and targeting to nuclear bodies.

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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DNA looping between the origin of replication of Epstein-Barr virus and its enhancer site: stabilization of an origin complex with Epstein-Barr nuclear antigen 1

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7 January 2021

Restricted expression of Epstein-Barr virus (EBV)-encoded, growth transformation-associated antigens in an EBV- and human herpesvirus type 8-carrying body cavity lymphoma line.

1 reference

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7 January 2021

A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells

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Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

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Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which Is mediated by the viral E2 protein and its binding sites

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Separation of the complex DNA binding domain of EBNA-1 into DNA recognition and dimerization subdomains of novel structure.

1 reference

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based on heuristic

inferred from DOI database lookup

Identification of EBNA1 amino acid sequences required for the interaction of the functional elements of the Epstein-Barr virus latent origin of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence requirements of the Epstein-Barr virus latent origin of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

based on heuristic

inferred from DOI database lookup

The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

based on heuristic

inferred from DOI database lookup

EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.002

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VIROL.2003.11.002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14980483%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14980483%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

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