(Q60345379)

English

High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma

scientific article published on 01 April 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17375124%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17375124%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Hodgkin lymphoma

1 reference

based on heuristic

inferred from title

mediastinal large B cell lymphoma

1 reference

based on heuristic

inferred from title

José I Martín-Subero

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17375124%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

9

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27 December 2019

author name string

Renné C

1

1 reference

Europe PubMed Central

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27 December 2019

Willenbrock K

2

1 reference

Europe PubMed Central

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27 December 2019

Hinsch N

4

1 reference

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27 December 2019

Döring C

5

1 reference

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27 December 2019

Tiacci E

6

1 reference

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27 December 2019

Klapper W

7

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27 December 2019

Möller P

8

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27 December 2019

Hansmann ML

10

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27 December 2019

Siebert R

11

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27 December 2019

Bräuninger A

12

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27 December 2019

publication date

1 April 2007

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27 December 2019

1 reference

Europe PubMed Central

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27 December 2019

21

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27 December 2019

4

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27 December 2019

780-787

1 reference

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27 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404594

0 references

Mediastinal (thymic) large B-cell lymphoma: where do we stand?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Isotype-switched immunoglobulin genes with a high load of somatic hypermutation and lack of ongoing mutational activity are prevalent in mediastinal B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

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Downregulation of internal enhancer activity contributes to abnormally low immunoglobulin expression in the MedB-1 mediastinal B-cell lymphoma cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

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Report: workshop on mediastinal grey zone lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Gain of chromosome arm 9p is characteristic of primary mediastinal B-cell lymphoma (MBL): comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Segmental chromosomal aberrations and centrosome amplifications: pathogenetic mechanisms in Hodgkin and Reed–Sternberg cells of classical Hodgkin's lymphoma?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Autocrine- and paracrine-activated receptor tyrosine kinases in classic Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

MedB-1, a human tumor cell line derived from a primary mediastinal large B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Cluster analysis and display of genome-wide expression patterns

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical screening for oncogenic tyrosine kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Two independent signaling pathways mediate the antiapoptotic action of macrophage-stimulating protein on epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

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Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.

1 reference

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7 January 2021

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Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

7 January 2021

based on heuristic

inferred from DOI database lookup

Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404594

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Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential

1 reference

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Genetics of myeloid malignancies: pathogenetic and clinical implications

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7 January 2021

based on heuristic

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Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma

1 reference

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Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

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Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor

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Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays

1 reference

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Tyrosine phosphorylation in human lymphomas.

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Selective activation of members of the signal transducers and activators of transcription family in prostate carcinoma

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