(Q60440984)

English

Prominent synaptic and metabolic abnormalities revealed by proteomic analysis of the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder

scientific article published on 16 October 2007

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8 January 2020

Prominent synaptic and metabolic abnormalities revealed by proteomic analysis of the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder (English)

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8 January 2020

bipolar disorder

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Kyla Pennington

1

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8 January 2020

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8 January 2020

Carmine Pariante

6

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8 January 2020

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8 January 2020

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P Dicker

3

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8 January 2020

A Fagan

4

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8 January 2020

J English

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8 January 2020

R Wait

7

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8 January 2020

M J Dunn

8

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8 January 2020

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16 October 2007

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8 January 2020

Molecular Psychiatry

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8 January 2020

13

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8 January 2020

12

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8 January 2020

1102-1117

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8 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.mp.4002098

0 references

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Cortical abnormalities in schizophrenia identified by structural magnetic resonance imaging.

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Subgenual prefrontal cortex abnormalities in mood disorders.

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Neuroimaging studies of mood disorder effects on the brain

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Decreased somal size of deep layer 3 pyramidal neurons in the prefrontal cortex of subjects with schizophrenia

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Neuronal and glial somal size in the prefrontal cortex: a postmortem morphometric study of schizophrenia and Huntington disease

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Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex

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Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia.

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Structural abnormalities of subicular dendrites in subjects with schizophrenia and mood disorders: preliminary findings

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Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia

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Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder.

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Multivariate analysis of prefrontal cortical data from the Stanley Foundation Neuropathology Consortium

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7 January 2021

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Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains

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Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

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Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

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Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia

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Application of cDNA microarrays to examine gene expression differences in schizophrenia

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Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

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Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia.

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Hippocampal complexin proteins and cognitive dysfunction in schizophrenia

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Schizophrenia: a genetic disorder of the synapse?

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The synaptic hypothesis of schizophrenia.

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A comparison of selected mRNA and protein abundances in human liver

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Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium

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Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

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A proteome analysis of the anterior cingulate cortex gray matter in schizophrenia.

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Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes.

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Mitochondrial related gene expression changes are sensitive to agonal-pH state

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Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions

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Postmortem changes in the level of brain proteins.

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Dihydropyrimidinase related protein-2 as a biomarker for temperature and time dependent post mortem changes in the mouse brain proteome

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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

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Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs

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Synaptic pathology in the anterior cingulate cortex in schizophrenia and mood disorders. A review and a Western blot study of synaptophysin, GAP-43 and the complexins

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Mutation analysis of SYNJ1: a possible candidate gene for chromosome 21q22-linked bipolar disorder

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Identification and molecular characterization of Unc-33-like phosphoprotein (Ulip), a putative mammalian homolog of the axonal guidance-associated unc-33 gene product.

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Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

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Intersectin regulates fission and internalization of caveolae in endothelial cells.

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Altered levels of the synaptosomal associated protein SNAP-25 in hippocampus of subjects with mood disorders and schizophrenia

1 reference

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SNAP-25 reduction in the hippocampus of patients with schizophrenia.

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Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of "neuroleptic-free" schizophrenics: evidence on reversible up-regulation by typical neuroleptics.

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Increased levels of expression of an NMDAR1 splice variant in the superior temporal gyrus in schizophrenia

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Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals

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Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia.

1 reference

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Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia.

1 reference

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A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.

1 reference

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Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population

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The emerging role of glutamate in the pathophysiology and treatment of schizophrenia

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Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder

1 reference

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NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder

1 reference

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Expression profiling the human septin gene family

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High rates of schizophrenia in adults with velo-cardio-facial syndrome.

1 reference

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7 January 2021

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Molecular characterization of deletion breakpoints in adults with 22q11 deletion syndrome

1 reference

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7 January 2021

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A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype

1 reference

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7 January 2021

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inferred from DOI database lookup

Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4.

1 reference

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7 January 2021

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The septin CDCrel-1 binds syntaxin and inhibits exocytosis

1 reference

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7 January 2021

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inferred from DOI database lookup

The septin Sept5/CDCrel-1 competes with alpha-SNAP for binding to the SNARE complex

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Differential localization of septins in the mouse brain

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of a novel septin protein, hCDCrel-1, in neurons of human brain

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of septins in neurofibrillary tangles in Alzheimer's disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

SEPT5_v2 is a parkin-binding protein

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Superoxide, neuroleptics and the ubiquinone and cytochrome b5 reductases in brain and lymphocytes from normals and schizophrenic patients

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial function is differentially altered in the basal ganglia of chronic schizophrenics

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002098

7 January 2021

based on heuristic

inferred from DOI database lookup

A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial dysfunction in bipolar disorder

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Regional cerebral glucose metabolic abnormalities in bipolar II depression.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Gene expression differences in bipolar disorder revealed by cDNA array analysis of post-mortem frontal cortex.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

An online database for brain disease research

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical localization of phosphorylated glial fibrillary acidic protein in the prefrontal cortex and hippocampus from patients with schizophrenia, bipolar disorder, and depression.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glial fibrillary acidic protein and glutamine synthetase in subregions of prefrontal cortex in schizophrenia and mood disorder.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.MP.4002098

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938637%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938637%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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