(Q60449866)

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26 December 2019

title

The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone (English)

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26 December 2019

1

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26 December 2019

Pertti J. Neuvonen

series ordinal

2

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26 December 2019

Janne Backman

series ordinal

3

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26 December 2019

publication date

11 July 2006

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European Journal of Clinical Pharmacology

26 December 2019

published in

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26 December 2019

volume

62

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26 December 2019

issue

8

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26 December 2019

page(s)

645-651

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Concentrations and effects of zopiclone are greatly reduced by rifampicin

26 December 2019

cites work

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12 December 2020

Pharmacokinetics and metabolism of zopiclone

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12 December 2020

Determination of gemfibrozil in plasma by high performance liquid chromatography

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12 December 2020

Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

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12 December 2020

Gemfibrozil greatly increases plasma concentrations of cerivastatin

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12 December 2020

Preparative and analytical separation of the zopiclone enantiomers and determination of their affinity to the benzodiazepine receptor binding site.

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12 December 2020

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone

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12 December 2020

Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes

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12 December 2020

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

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12 December 2020

Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.

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12 December 2020

Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance

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12 December 2020

Cytochrome P-450 3A4 and 2C8 are involved in zopiclone metabolism.

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12 December 2020

Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

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12 December 2020

Zopiclone. An update of its pharmacology, clinical efficacy and tolerability in the treatment of insomnia

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12 December 2020

Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite

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12 December 2020

Zopiclone. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy as an hypnotic

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12 December 2020

Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers.

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12 December 2020

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

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12 December 2020

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

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12 December 2020

Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions

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12 December 2020

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone

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12 December 2020

The effect of erythromycin on the pharmacokinetics and pharmacodynamics of zopiclone

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12 December 2020

Clinical pharmacokinetics of zopiclone

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12 December 2020

Selective inhibition of human cytochrome P4502C8 by montelukast

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12 December 2020

10.1007/S00228-006-0155-6

Identifiers

DOI

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26 December 2019

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