(Q60644555)

English

Drug action at the 5-HT1A receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-11C]WAY-100635

scientific article published on 01 July 2000

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scholarly article

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9 November 2019

Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635 (English)

1 reference

Europe PubMed Central

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9 November 2019

2

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9 November 2019

7

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9 November 2019

author name string

E A Rabiner

1

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9 November 2019

M R Wilkins

3

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9 November 2019

P A Sargent

4

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9 November 2019

E Mocaer

5

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9 November 2019

E Sedman

6

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9 November 2019

P M Grasby

8

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9 November 2019

publication date

1 July 2000

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9 November 2019

Nuclear Medicine and Biology

1 reference

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9 November 2019

27

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9 November 2019

5

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9 November 2019

509-513

1 reference

Europe PubMed Central

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9 November 2019

Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. An in vivo brain microdialysis study.

1 reference

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Effect of pindolol on endocrine and temperature responses to buspirone in healthy volunteers

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Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists.

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Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo

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Neuroendocrine effects of azapirones.

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5-HT1A receptor agonists: recent developments and controversial issues

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Pustative anxiolytics 8-OH-DPAT, buspirone and TVX Q 7821 are agonists at 5-HT1A autoreceptors in the raphé nuclei

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Plastic transformation of PET images.

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Role of 5-HT in stress, anxiety, and depression.

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7 January 2021

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Correction for scatter in 3D brain PET using a dual energy window method.

1 reference

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7 January 2021

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Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C]WAY-100635 for PET.

1 reference

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7 January 2021

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Parametric imaging of ligand-receptor binding in PET using a simplified reference region model.

1 reference

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7 January 2021

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Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635

1 reference

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7 January 2021

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Pindolol occupancy of 5-HT(1A) receptors measured in vivo using small animal positron emission tomography with carbon-11 labeled WAY 100635

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Is pindolol a mixed agonist-antagonist at central serotonin (5-HT) receptors?

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7 January 2021

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Administration of 8-hydroxy-2-(Di-n-propylamino)tetralin in raphe nuclei dorsalis and medianus reduces serotonin synthesis in the rat brain: differences in potency and regional sensitivity

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Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex.

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Assessment of spatial normalization of PET ligand images using ligand-specific templates.

1 reference

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7 January 2021

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S 15535: a highly selective benzodioxopiperazine 5-HT1A receptor ligand which acts as an agonist and an antagonist at presynaptic and postsynaptic sites respectively

1 reference

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7 January 2021

based on heuristic

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S 15535 and WAY 100,635 antagonise 5-HT-stimulated [35S]GTP gamma S binding at cloned human 5-HT1A receptors

1 reference

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7 January 2021

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A double-blind, randomized, placebo-controlled trial of pindolol augmentation in depressive patients resistant to serotonin reuptake inhibitors. Grup de Recerca en Trastorns Afectius.

1 reference

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7 January 2021

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Selective labeling of 5-HT1A and 5-HT1B binding sites in bovine brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2800%2900120-7

7 January 2021

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Displacement of the binding of 5-HT1A receptor ligands to pre- and postsynaptic receptors by (-)pindolol. A comparative study in rodent, primate and human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2800%2900120-7

7 January 2021

based on heuristic

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Assessment of relative efficacies of 5-HT1A receptor ligands by means of in vivo animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2800%2900120-7

7 January 2021

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5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2800%2900120-7

7 January 2021

based on heuristic

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Electrophysiological evidence for a functional differentiation between subtypes of the 5-HT1 receptor

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The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamino)tetralin in the rat.

1 reference

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7 January 2021

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Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug.

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Identifiers

10.1016/S0969-8051(00)00120-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10962259%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Europe PubMed Central

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9 November 2019

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