(Q60777352)

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Inactivation of the Cerebral NFκB Pathway Inhibits Interleukin-1β-Induced Sickness Behavior and c-Fos Expression in Various Brain Nuclei

scientific article published on 01 August 2005

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scholarly article

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11 January 2020

Inactivation of the cerebral NFkappaB pathway inhibits interleukin-1beta-induced sickness behavior and c-Fos expression in various brain nuclei (English)

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11 January 2020

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11 January 2020

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11 January 2020

author name string

Rose-Marie Bluthé

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11 January 2020

Patricia Parnet

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1 August 2005

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11 January 2020

Neuropsychopharmacology

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11 January 2020

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11 January 2020

1492-1499

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11 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.npp.1300755

0 references

Function and activation of NF-kappa B in the immune system

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Vagotomy attenuates behavioural effects of interleukin-1 injected peripherally but not centrally.

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Cytokine-induced sickness behavior: mechanisms and implications

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Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity.

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Cytokines, stress, and depression. Conclusions and perspectives

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Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis

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Differential pattern of c-fos mRNA in rat brain following central and systemic administration of interleukin-1-beta: implications for mechanism of action.

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The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1.

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A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons.

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Type 1 interleukin-1 receptor in the rat brain: distribution, regulation, and relationship to sites of IL-1-induced cellular activation.

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Acute-phase proteins and other systemic responses to inflammation

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Signaling to NF-kappaB

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Temporal and spatial patterns of c-fos mRNA induced by intravenous interleukin-1: a cascade of non-neuronal cellular activation at the blood-brain barrier.

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Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1

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How the immune and nervous systems interact during disease-associated anorexia.

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Diffusion and action of intracerebroventricularly injected interleukin-1 in the CNS.

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Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli

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Humoral regulation of physiological sleep: cytokines and GHRH.

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Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain.

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An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia

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Role of corticosterone in the behavioral effects of central interleukin-1 beta.

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Identifiers

10.1038/SJ.NPP.1300755

1 reference

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1 reference

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11 January 2020

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