(Q60956725)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30619752%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

title

Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation (English)

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18 April 2020

7

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18 April 2020

author name string

Zachary S Buchwald

1

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18 April 2020

Jacob Wynne

2

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18 April 2020

Tahseen H Nasti

3

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18 April 2020

Simeng Zhu

4

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18 April 2020

Waleed F Mourad

5

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18 April 2020

Weisi Yan

6

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18 April 2020

Samir N Khleif

8

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18 April 2020

Mohammad K Khan

9

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18 April 2020

language of work or name

English

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publication date

13 December 2018

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18 April 2020

published in

Frontiers in Oncology

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18 April 2020

volume

8

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18 April 2020

page(s)

612

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Creative Commons Attribution 4.0 International

18 April 2020

copyright license

start time

13 December 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The Abscopal Effect in Malignant Lymphoma and Its Relationship to Lymphocyte Circulation

1 reference

12 December 2020

Spontaneous regression of metastatic renal cell carcinoma following palliative irradiation of the primary tumour

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12 December 2020

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

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12 December 2020

Enhancement of antitumor immunity by CTLA-4 blockade

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12 December 2020

Dendritic cells at the end of the millennium

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12 December 2020

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

1 reference

12 December 2020

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

1 reference

12 December 2020

Whole body irradiation; radiobiology or medicine?

1 reference

12 December 2020

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

1 reference

12 December 2020

Spontaneous regression of a large hepatocellular carcinoma with skull metastasis.

1 reference

12 December 2020

Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor

1 reference

12 December 2020

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

12 December 2020

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

1 reference

12 December 2020

Checkpoint blockade in cancer immunotherapy

1 reference

12 December 2020

Calreticulin exposure dictates the immunogenicity of cancer cell death

1 reference

12 December 2020

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

1 reference

12 December 2020

Role of tumor necrosis factor-alpha and TRAIL in high-dose radiation-induced bystander signaling in lung adenocarcinoma

1 reference

12 December 2020

How dying cells alert the immune system to danger

1 reference

12 December 2020

A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status

1 reference

12 December 2020

Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody

1 reference

12 December 2020

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

1 reference

12 December 2020

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

1 reference

12 December 2020

Maximizing tumor immunity with fractionated radiation

1 reference

12 December 2020

Radiation-induced vascular damage in tumors: implications of vascular damage in ablative hypofractionated radiotherapy (SBRT and SRS).

1 reference

12 December 2020

Immunologic correlates of the abscopal effect in a patient with melanoma

1 reference

12 December 2020

Phase 1 study of stereotactic body radiotherapy and interleukin-2--tumor and immunological responses

1 reference

12 December 2020

The convergence of radiation and immunogenic cell death signaling pathways.

1 reference

12 December 2020

Role of lymphocytic choriomeningitis virus (LCMV) in understanding viral immunology: past, present and future

1 reference

12 December 2020

Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study

1 reference

12 December 2020

Abscopal Effects after Conventional and Stereotactic Lung Irradiation of Non–Small-Cell Lung Cancer

1 reference

12 December 2020

Radiation and immunotherapy: a synergistic combination.

1 reference

12 December 2020

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

1 reference

12 December 2020

Norm- and hypo-fractionated radiotherapy is capable of activating human dendritic cells

1 reference

12 December 2020

In vivo effects of lattice radiation therapy on local and distant lung cancer: potential role of immunomodulation

1 reference

12 December 2020

TGFβ inhibition prior to hypofractionated radiation enhances efficacy in preclinical models

1 reference

12 December 2020

Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade.

1 reference

12 December 2020

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

1 reference

12 December 2020

Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment.

1 reference

12 December 2020

Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial.

1 reference

12 December 2020

Systematic review of case reports on the abscopal effect

1 reference

12 December 2020

Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease

1 reference

12 December 2020

Key Role of DAMP in Inflammation, Cancer, and Tissue Repair

1 reference

12 December 2020

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

1 reference

12 December 2020

Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial

1 reference

12 December 2020

Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy

1 reference

12 December 2020

Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery

1 reference

12 December 2020

Checkpoint Antibodies but not T Cell-Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation.

1 reference

12 December 2020

Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release

1 reference

12 December 2020

Safety and Efficacy of Radiation Therapy in Advanced Melanoma Patients Treated With Ipilimumab

1 reference

12 December 2020

Current clinical trials testing the combination of immunotherapy with radiotherapy.

1 reference

12 December 2020

Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer

1 reference

12 December 2020

Immunogenic cell death in cancer and infectious disease

1 reference

12 December 2020

Chemoradiation Increases PD-L1 Expression in Certain Melanoma and Glioblastoma Cells

1 reference

12 December 2020

cGAS is essential for the antitumor effect of immune checkpoint blockade

1 reference

12 December 2020

Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors.

1 reference

12 December 2020

Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial.

1 reference

12 December 2020

Multicenter Evaluation of the Tolerability of Combined Treatment With PD-1 and CTLA-4 Immune Checkpoint Inhibitors and Palliative Radiation Therapy

1 reference

12 December 2020

Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial.

1 reference

12 December 2020

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

1 reference

12 December 2020

Hunting for abscopal and bystander effects: clinical exploitation of non-targeted effects induced by partial high-single-dose irradiation of the hypoxic tumour segment in oligometastatic patients

1 reference

12 December 2020

Efficacy and Safety of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma: Updated Results From a Phase 1/2 Open-label Study.

1 reference

12 December 2020

TREX1 dictates the immune fate of irradiated cancer cells.

1 reference

12 December 2020

Chemoradiation-Induced Alteration of Programmed Death-Ligand 1 and CD8+ Tumor-Infiltrating Lymphocytes Identified Patients With Poor Prognosis in Rectal Cancer: A Matched Comparison Analysis

1 reference

12 December 2020

PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation.

1 reference

12 December 2020

CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions.

1 reference

12 December 2020

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

1 reference

12 December 2020

Using immunotherapy to boost the abscopal effect.

1 reference

12 December 2020

Abscopal Effects With Hypofractionated Schedules Extending Into the Effector Phase of the Tumor-Specific T-Cell Response.

1 reference

12 December 2020

Role of PD-1 during effector CD8 T cell differentiation.

1 reference

12 December 2020

Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC

1 reference

12 December 2020

Immunotherapy and Radiation - A New Combined Treatment Approach for Bladder Cancer?

1 reference

12 December 2020

Identifiers

DOI

10.3389/FONC.2018.00612

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30619752%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

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18 April 2020

PubMed publication ID

30619752

1 reference