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Dominant transplantation tolerance impairs CD8+ T cell function but not expansion
scientific article published on 04 November 2002
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scholarly article
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Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
title
Dominant transplantation tolerance impairs CD8+ T cell function but not expansion
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
main subject
cell function
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author
Chun-Yen Lin
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Luis Graca
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2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Stephen P. Cobbold
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3
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Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Herman Waldmann
series ordinal
4
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Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
language of work or name
English
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publication date
4 November 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
published in
Nature Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
volume
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
page(s)
1208-1213
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/ni853
0 references
cites work
"Infectious" transplantation tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How do monoclonal antibodies induce tolerance? A role for infectious tolerance?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
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inferred from DOI database lookup
TOLERANCE AND SUPPRESSION IN A PRIMED IMMUNE SYSTEM1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential function of major histocompatibility complex antigens in T-lymphocyte activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulating the immune response to transplants. a role for CD4+ regulatory cells?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral immune evasion due to persistence of activated T cells without effector function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Determinants of viral clearance and persistence during acute hepatitis C virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of different antigenic microenvironments on the course of CD8+ T cell responses in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells overexpress a subset of Th2 gene transcripts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Actively acquired tolerance of foreign cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of tolerance in peripheral T cells with monoclonal antibodies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of intracellular cytokines by flow cytometry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The JAM test. A simple assay for DNA fragmentation and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI853
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NI853
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Dimensions Publication ID
1022553373
0 references
PubMed publication ID
12415266
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12415266
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12415266%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
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