(Q61804929)

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Grape Seed Proanthocyanidin Extract Alleviates AflatoxinB₁-Induced Immunotoxicity and Oxidative Stress via Modulation of NF-κB and Nrf2 Signaling Pathways in Broilers

scientific article published on 07 January 2019

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18 April 2020

Grape Seed Proanthocyanidin Extract Alleviates AflatoxinB₁-Induced Immunotoxicity and Oxidative Stress via Modulation of NF-κB and Nrf2 Signaling Pathways in Broilers (English)

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18 April 2020

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NRF2 [nucleoplasm]

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Shahid Ali Rajput

1

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18 April 2020

Mahmoud Mohamed Khalil

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18 April 2020

Farhan Anwar Khan

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18 April 2020

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Lvhui Sun

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18 April 2020

Ni-Ya Zhang

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18 April 2020

Zhao Ling

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18 April 2020

Li Chong

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18 April 2020

Shuai Wang

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18 April 2020

Imran Rashid Rajput

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18 April 2020

Dost Muhammad Bloch

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18 April 2020

Aftab Shaukat

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18 April 2020

Desheng Qi

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18 April 2020

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7 January 2019

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18 April 2020

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18 April 2020

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18 April 2020

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18 April 2020

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Creative Commons Attribution 4.0 International

7 January 2019

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0 references

Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Aflatoxin B1-induced lipid peroxidation in rat liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Heme oxygenase: colors of defense against cellular stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Analgesic and anti-inflammatory activity of the proanthocyanidin shellegueain A from Polypodium feei METT.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Xenotransplantation: just around the corner?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Liver carcinogen aflatoxin B1 as an inducer of mitotic recombination in a human cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Lipopolysaccharide recognition, internalisation, signalling and other cellular effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Antioxidants and radical scavenging properties of vegetable extracts in rats fed aflatoxin-contaminated diet.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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Modulatory effects of selenium and zinc on the immune system

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https://pubmed.ncbi.nlm.nih.gov/30621062

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Nitric oxide and superoxide in inflammation and immune regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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Cytotoxicity of occupationally and environmentally relevant mycotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Nrf2 as a novel molecular target for chemoprevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Carnosic acid from rosemary extracts: a potential chemoprotective agent against aflatoxin B1. An in vitro study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Effects of marjoram volatile oil and grape seed extract on ethanol toxicity in male rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Immunotoxicity of aflatoxin B1: impairment of the cell-mediated response to vaccine antigen and modulation of cytokine expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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The nuclear factor NF-kappaB pathway in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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Aflatoxin B1 in poultry: toxicology, metabolism and prevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Key roles of vitamins A, C, and E in aflatoxin B1-induced oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Spleen transcriptome response to infection with avian pathogenic Escherichia coli in broiler chickens

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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An overview of cancer chemopreventive potential and safety of proanthocyanidins

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Aflatoxin B(1) in affecting broiler's performance, immunity, and gastrointestinal tract: a review of history and contemporary issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

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Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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NF-κB, the first quarter-century: remarkable progress and outstanding questions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Aflatoxins: biosynthesis, occurrence, toxicity, and remedies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape seed proanthocyanidin extract protects against carrageenan-induced lung inflammation in mice through reduction of pro-inflammatory markers and chemokine expressions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

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Recent updates on acetaminophen hepatotoxicity: the role of nrf2 in hepatoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

inferred from PubMed ID database lookup

Effects of lipoic acid on immune function, the antioxidant defense system, and inflammation-related genes expression of broiler chickens fed aflatoxin contaminated diets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

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Antioxidant properties of proanthocyanidins attenuate carbon tetrachloride (CCl4)-induced steatosis and liver injury in rats via CYP2E1 regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

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Effects of grape seed proanthocyanidin extract on pentylenetetrazole-induced kindling and associated cognitive impairment in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatotoxic effects of mycotoxin combinations in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape seed proanthocyanidin protects liver against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Mechanisms of Lipoic Acid Protection against Aflatoxin B₁-Induced Liver Oxidative Damage and Inflammatory Responses in Broilers

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intervention of Grape Seed Proanthocyanidin Extract on the Subchronic Immune Injury in Mice Induced by Aflatoxin B1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protective Effect of Grape-Seed Proanthocyanidin Extract on Oxidative Damage Induced by Zearalenone in Kunming Mice Liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Nutrients in Substrates of Different Grains on Aflatoxin B1 Production by Aspergillus flavus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

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1 reference

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based on heuristic

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Curcumin Prevents Aflatoxin B₁ Hepatoxicity by Inhibition of Cytochrome P450 Isozymes in Chick Liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of phenolics rich extract of ginger against Aflatoxin B1-induced oxidative stress and hepatotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomeric proanthocyanidins protects A549 cells against H2O2-induced oxidative stress via the Nrf2-ARE pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

inferred from PubMed ID database lookup

Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

1 reference

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based on heuristic

inferred from PubMed ID database lookup

NF-kappa B activation correlates with disease phenotype in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ameliorative Effects of Grape Seed Proanthocyanidin Extract on Growth Performance, Immune Function, Antioxidant Capacity, Biochemical Constituents, Liver Histopathology and Aflatoxin Residues in Broilers Exposed to Aflatoxin B₁.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotoxicity of ochratoxin A and aflatoxin B1 in combination is associated with the nuclear factor kappa B signaling pathway in 3D4/21 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

inferred from PubMed ID database lookup

Sensitivity of Arbor Acres broilers and chemoprevention of aflatoxin B-induced liver injury by curcumin, a natural potent inducer of phase-II enzymes and Nrf2

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

inferred from PubMed ID database lookup

Prenatal exposure to zearalenone disrupts reproductive potential and development via hormone-related genes in male rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621062

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based on heuristic

inferred from PubMed ID database lookup

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10.3390/TOXINS11010023

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18 April 2020

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18 April 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30621062%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

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