(Q62582720)

English

Intermolecular and Intramolecular Hydrogen Bonds Involving Fluorine Atoms: Implications for Recognition, Selectivity, and Chemical Properties

scientific article published on 19 January 2012

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Intermolecular and intramolecular hydrogen bonds involving fluorine atoms: implications for recognition, selectivity, and chemical properties (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

molecular medicine

0 references

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Claudio Dalvit

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

19 January 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

262-272

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Understanding organofluorine chemistry. An introduction to the C-F bond

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorine-protein interactions and ¹⁹F NMR isotropic chemical shifts: An empirical correlation with implications for drug design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Design and NMR-based screening of LEF, a library of chemical fragments with different local environment of fluorine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

The Cambridge Structural Database: a quarter of a million crystal structures and rising

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

New software for searching the Cambridge Structural Database and visualizing crystal structures

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular Pair Analysis: CH⋅⋅⋅F Interactions in the Crystal Structure of Fluorobenzene? And Related Matters

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Energetically important C-H···F-C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Determinants of the unexpected stability of RNA fluorobenzene self pairs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleobase-fluorobenzene interactions: hydrogen bonding wins over pi stacking

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

19F NMR chemical shift prediction with fluorine fingerprint descriptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleophilic substitution reactions of sulfur-substituted cyclohexanone acetals: an analysis of the factors controlling stereoselectivity.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

1-De-oxy-1-fluoro-l-galactitol

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorinated phenylcyclopropylamines. Part 4: effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-aryl-2-fluoro-cyclopropylamines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

The vicinal difluoro motif: The synthesis and conformation of erythro- and threo- diastereoisomers of 1,2-difluorodiphenylethanes, 2,3-difluorosuccinic acids and their derivatives

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

DL-threo-beta-Fluoroaspartate and DL-threo-beta-fluoroasparagine: selective cytotoxic agents for mammalian cells in culture

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Complete relative stereochemistry of multiple stereocenters using only residual dipolar couplings

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Cooperative effects in hydrogen-bonding of protein secondary structure elements: a systematic analysis of crystal data using Secbase.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorine in pharmaceuticals: looking beyond intuition

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Parametrization of Substituents: Effects of Fluorine and Other Heteroatoms on OH, NH, and CH Acidities

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Intramolecular hydrogen bonding in medicinal chemistry

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

N-H...F hydrogen bonds in fluorinated benzanilides: NMR and DFT study

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

A bond by any other name

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Matched molecular pairs as a medicinal chemistry tool

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: exploration of effective compounds in arthritis models.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural Basis for the Activity and Substrate Specificity of Fluoroacetyl-CoA Thioesterase FlK

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Organic Fluorine Hardly Ever Accepts Hydrogen Bonds

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

( R )-β,γ-Fluoromethylene-dGTP-DNA Ternary Complex with DNA Polymerase β

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Halogenated β,γ-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase β: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

The coordination chemistry of fluorine in fluorocarbons.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping the Reaction Coordinates of Enzymatic Defluorination

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure and mechanism of a bacterial fluorinating enzyme

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201100483

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CMDC.201100483

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262517%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q62582720&oldid=1675836145"