(Q6393589)

English

Keratin 14

mammalian protein found in Homo sapiens

CK-14
keratin 14, type I
keratin, type I cytoskeletal 14
K14
cytokeratin 14
Cytokeratin-14
Keratin-14
KRT14

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

keratin, type I

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02533

Intermediate filament, rod domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Intermediate filament protein, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

structural constituent of cytoskeleton

determination method

1 reference

8 April 2019

A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

protein binding

determination method

6 references

8 April 2019

Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Characterization of human epiplakin: RNAi-mediated epiplakin depletion leads to the disruption of keratin and vimentin IF networks

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Identification of trichoplein, a novel keratin filament-binding protein

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

keratin filament binding

determination method

1 reference

8 April 2019

Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

structural molecule activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

extracellular exosome

determination method

1 reference

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02533&geneProductId=UniProtKB:P02533

determination method

intermediate filament

determination method

3 references

intracellular anatomical structure

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02533&geneProductId=UniProtKB:P02533

determination method

determination method

3 references

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02533&geneProductId=UniProtKB:P02533

determination method

17 October 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02533&geneProductId=UniProtKB:P02533

determination method

17 October 2017

The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02533&geneProductId=UniProtKB:P02533

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

basal part of cell

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

biological process

response to ionizing radiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

hemidesmosome assembly

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

1 reference

8 April 2019

Hair greying is associated with active hair growth

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

1 reference

8 April 2019

Hair greying is associated with active hair growth

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

response to zinc ion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

epithelial cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

intermediate filament bundle assembly

determination method

1 reference

8 April 2019

The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

epidermis development

determination method

1 reference

8 April 2019

A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02533

determination method

Gene Atlas image

PBB GE KRT14 209351 at fs.png
732 × 530; 11 KB

0 references

Intermediate filament protein, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02533

Intermediate filament, rod domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02533

Identifiers

MeSH descriptor ID

subject named as

Keratin-14

0 references

D05.750.078.593.450.300.400

0 references

D12.776.220.475.450.300.400

0 references

D12.776.860.607.300.400

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000167586

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000167586

PDB structure ID

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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