(Q64260377)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

title

Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

alternative mRNA splicing, via spliceosome

24 April 2020

main subject

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

author name string

Lavinia A Carabet

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Nada Lallous

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Helene Morin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Fariba Ghaidi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Joseph Lee

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Paul S Rennie

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Artem Cherkasov

8

1 reference

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24 April 2020

language of work or name

English

0 references

publication date

20 February 2019

1 reference

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24 April 2020

1 reference

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24 April 2020

volume

24

1 reference

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24 April 2020

issue

4

1 reference

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Creative Commons Attribution 4.0 International

24 April 2020

page(s)

763

0 references

copyright license

start time

20 February 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro

1 reference

12 December 2020

Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.

1 reference

12 December 2020

Quercetin inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells

1 reference

12 December 2020

hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis

1 reference

12 December 2020

Kinase inhibitors: not just for kinases anymore

1 reference

12 December 2020

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

1 reference

12 December 2020

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

1 reference

12 December 2020

ZINC--a free database of commercially available compounds for virtual screening

1 reference

12 December 2020

Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling

1 reference

12 December 2020

IL-6-induced stimulation of c-myc translation in multiple myeloma cells is mediated by myc internal ribosome entry site function and the RNA-binding protein, hnRNP A1.

1 reference

12 December 2020

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

1 reference

12 December 2020

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

1 reference

12 December 2020

The VSGB 2.0 model: a next generation energy model for high resolution protein structure modeling

1 reference

12 December 2020

Quantifying the chemical beauty of drugs.

1 reference

12 December 2020

hnRNP A1 proofreads 3' splice site recognition by U2AF.

1 reference

12 December 2020

Docking and scoring with ICM: the benchmarking results and strategies for improvement

1 reference

12 December 2020

ZINC: a free tool to discover chemistry for biology

1 reference

12 December 2020

FRED and HYBRID docking performance on standardized datasets.

1 reference

12 December 2020

Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.

1 reference

12 December 2020

Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines

1 reference

12 December 2020

EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer

1 reference

12 December 2020

Mechanisms of the androgen receptor splicing in prostate cancer cells

1 reference

12 December 2020

hnRNP A1: the Swiss army knife of gene expression

1 reference

12 December 2020

Maintaining and reprogramming genomic androgen receptor activity in prostate cancer

1 reference

12 December 2020

Thermodynamic and phylogenetic insights into hnRNP A1 recognition of the HIV-1 exon splicing silencer 3 element

1 reference

12 December 2020

The role of mRNA splicing in prostate cancer

1 reference

12 December 2020

Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells.

1 reference

12 December 2020

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer

1 reference

12 December 2020

Chemistry: Chemical con artists foil drug discovery

1 reference

12 December 2020

Generation 2.5 antisense oligonucleotides targeting the androgen receptor and its splice variants suppress enzalutamide-resistant prostate cancer cell growth

1 reference

12 December 2020

The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities

1 reference

12 December 2020

Targeting the adaptive molecular landscape of castration-resistant prostate cancer

1 reference

12 December 2020

A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants

1 reference

12 December 2020

The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein

1 reference

12 December 2020

NF-κB2/p52:c-Myc:hnRNPA1 Pathway Regulates Expression of Androgen Receptor Splice Variants and Enzalutamide Sensitivity in Prostate Cancer

1 reference

12 December 2020

CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer.

1 reference

12 December 2020

ZINC 15--Ligand Discovery for Everyone

1 reference

12 December 2020

Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer

1 reference

12 December 2020

Knockdown of HNRNPA1 inhibits lung adenocarcinoma cell proliferation through cell cycle arrest at G0/G1 phase

1 reference

12 December 2020

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

1 reference

12 December 2020

MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma

1 reference

12 December 2020

Targeting MYC in cancer therapy: RNA processing offers new opportunities

1 reference

12 December 2020

Quercetin induces cell apoptosis of myeloma and displays a synergistic effect with dexamethasone in vitro and in vivo xenograft models

1 reference

12 December 2020

Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's Lymphoma.

1 reference

12 December 2020

Emerging data on androgen receptor splice variants in prostate cancer

1 reference

12 December 2020

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.

1 reference

12 December 2020

Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution

1 reference

12 December 2020

c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks

1 reference

12 December 2020

Quercetin Targets hnRNPA1 to Overcome Enzalutamide Resistance in Prostate Cancer Cells

1 reference

12 December 2020

Emerging roles of hnRNPA1 in modulating malignant transformation.

1 reference

12 December 2020

High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer.

1 reference

12 December 2020

HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo

1 reference

12 December 2020

Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer

1 reference

12 December 2020

Therapeutic Inhibition of Myc in Cancer. Structural Bases and Computer-Aided Drug Discovery Approaches

1 reference

12 December 2020

10.3390/MOLECULES24040763

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30791548%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference