(Q64265673)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

title

Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

0 references

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Streptococcus pneumoniae

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4

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27 April 2020

Asparouh I Iliev

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

author name string

Sabrina Hupp

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

Denis Grandgirard

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

Timothy J Mitchell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

Lucy J Hathaway

5

1 reference

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27 April 2020

language of work or name

English

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publication date

18 May 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neuroinflammation

27 April 2020

published in

1 reference

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27 April 2020

volume

16

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27 April 2020

page(s)

105

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27 April 2020

issue

1

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describes a project that uses

27 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6525981/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 December 2020

Inhibition of macrophage migration by normal guinea pig intestinal secretions

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Different effects of native Candida albicans mannan and mannan-derived oligosaccharides on antigen-stimulated lymphoproliferation in vitro

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Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice.

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Spectrum of complications during bacterial meningitis in adults. Results of a prospective clinical study.

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ATP released from astrocytes mediates glial calcium waves

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12 December 2020

Relationship between cell surface carbohydrates and intrastrain variation on opsonophagocytosis of Streptococcus pneumoniae.

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12 December 2020

Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations

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12 December 2020

Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis.

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12 December 2020

Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor

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12 December 2020

Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.

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12 December 2020

Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis

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12 December 2020

Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone

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12 December 2020

Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9).

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12 December 2020

CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection.

1 reference

12 December 2020

Cdc42 and RhoB activation are required for mannose receptor-mediated phagocytosis by human alveolar macrophages

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12 December 2020

Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination

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12 December 2020

ATP mediates rapid microglial response to local brain injury in vivo

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12 December 2020

Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells

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12 December 2020

The mechanism of pneumolysin-induced cochlear hair cell death in the rat.

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12 December 2020

Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice.

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12 December 2020

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin

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12 December 2020

Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo

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12 December 2020

Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis.

1 reference

12 December 2020

Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking.

1 reference

12 December 2020

Glutamate induces directed chemotaxis of microglia.

1 reference

12 December 2020

Adenosine A(2A) receptor mediates microglial process retraction

1 reference

12 December 2020

The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanisms

1 reference

12 December 2020

African meningitis belt pneumococcal disease epidemiology indicates a need for an effective serotype 1 containing vaccine, including for older children and adults

1 reference

12 December 2020

Diffuse cerebral intravascular coagulation and cerebral infarction in pneumococcal meningitis.

1 reference

12 December 2020

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

1 reference

12 December 2020

Olfactory ensheathing cells as putative host cells for Streptococcus pneumoniae: evidence of bacterial invasion via mannose receptor-mediated endocytosis

1 reference

12 December 2020

Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue

1 reference

12 December 2020

Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema.

1 reference

12 December 2020

Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity

1 reference

12 December 2020

Quantitative mapping of averaged focal adhesion dynamics in migrating cells by shape normalization

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12 December 2020

Capsule type of Streptococcus pneumoniae determines growth phenotype

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12 December 2020

C-type lectin receptors orchestrate antifungal immunity

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12 December 2020

Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin

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12 December 2020

Review: activation patterns of microglia and their identification in the human brain.

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12 December 2020

Mechanotransduction at focal adhesions: integrating cytoskeletal mechanics in migrating cells

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12 December 2020

The brain's best friend: microglial neurotoxicity revisited

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12 December 2020

Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage.

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12 December 2020

The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion

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12 December 2020

Contribution of different pneumococcal virulence factors to experimental meningitis in mice.

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12 December 2020

Imaging microglia in brain slices and slice cultures.

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12 December 2020

The pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tract

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12 December 2020

Exploitation of the Macrophage Mannose Receptor (CD206) in Infectious Disease Diagnostics and Therapeutics.

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12 December 2020

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia

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12 December 2020

Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion

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12 December 2020

Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis.

1 reference

12 December 2020

Matrix metalloproteinase-9 plays a role in protecting zebrafish from lethal infection with Listeria monocytogenes by enhancing macrophage migration

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12 December 2020

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model.

1 reference

12 December 2020

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

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12 December 2020

Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes

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12 December 2020

M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1.

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12 December 2020

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke.

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12 December 2020

Epidemiology of community-acquired bacterial meningitis.

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12 December 2020

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival

1 reference

12 December 2020

10.1186/S12974-019-1491-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31103037%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

1 reference