(Q64267066)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30714733%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

title

Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain (English)

1 reference

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21 April 2020

0 references

1 reference

1

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21 April 2020

Tristan Rawling

2

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21 April 2020

Subhodeep Sarker

6

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21 April 2020

Renae M. Ryan

9

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21 April 2020

Robert J. Vandenberg

11

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21 April 2020

author name string

Sarasa Mohammadi

3

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21 April 2020

Susan Shimmon

4

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21 April 2020

Zachary J Frangos

5

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21 April 2020

Arsalan Yousuf

7

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21 April 2020

Irina Vetter

8

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21 April 2020

Macdonald J Christie

10

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21 April 2020

language of work or name

English

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publication date

20 February 2019

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Journal of Medicinal Chemistry

21 April 2020

published in

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21 April 2020

volume

62

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21 April 2020

page(s)

2466-2484

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21 April 2020

issue

5

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A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

21 April 2020

cites work

1 reference

12 December 2020

Glycine transporters are differentially expressed among CNS cells.

1 reference

12 December 2020

Quantitative assessment of tactile allodynia in the rat paw

1 reference

12 December 2020

(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability

1 reference

12 December 2020

N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite

1 reference

12 December 2020

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

1 reference

12 December 2020

Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions.

1 reference

12 December 2020

Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome

1 reference

12 December 2020

Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability.

1 reference

12 December 2020

Cannabinoid penetration into mouse brain as determined by ex vivo binding.

1 reference

12 December 2020

The first potent and selective inhibitors of the glycine transporter type 2.

1 reference

12 December 2020

Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

1 reference

12 December 2020

Non-hydrogen bond interactions involving the methionine sulfur atom.

1 reference

12 December 2020

Regulation of anandamide tissue levels by N-arachidonylglycine

1 reference

12 December 2020

Influence of nonspecific brain and plasma binding on CNS exposure: implications for rational drug discovery.

1 reference

12 December 2020

Clinical Effectiveness and Cost-Effectiveness of Treatments for Patients With Chronic Pain

1 reference

12 December 2020

Inhibitors of GlyT1 and GlyT2 differentially modulate inhibitory transmission

1 reference

12 December 2020

N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a.

1 reference

12 December 2020

Molecular basis for substrate discrimination by glycine transporters.

1 reference

12 December 2020

Actions of N-arachidonyl-glycine in a rat neuropathic pain model

1 reference

12 December 2020

Actions of N-arachidonyl-glycine in a rat inflammatory pain model

1 reference

12 December 2020

Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice

1 reference

12 December 2020

Biosynthesis, degradation and pharmacological importance of the fatty acid amides

1 reference

12 December 2020

Opioids and the treatment of chronic pain: controversies, current status, and future directions

1 reference

12 December 2020

Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain

1 reference

12 December 2020

Neuropathic pain: a maladaptive response of the nervous system to damage

1 reference

12 December 2020

Central sensitization: a generator of pain hypersensitivity by central neural plasticity

1 reference

12 December 2020

The antinociceptive effect of intrathecal administration of glycine transporter-2 inhibitor ALX1393 in a rat acute pain model

1 reference

12 December 2020

Glycinergic and GABAergic tonic inhibition fine tune inhibitory control in regionally distinct subpopulations of dorsal horn neurons

1 reference

12 December 2020

N-arachidonyl-glycine modulates synaptic transmission in superficial dorsal horn

1 reference

12 December 2020

Neuronal circuitry for pain processing in the dorsal horn

1 reference

12 December 2020

Conus venom peptide pharmacology

1 reference

12 December 2020

Oleoyl-L-carnitine inhibits glycine transport by GlyT2

1 reference

12 December 2020

N-Acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids - from fishy endocannabinoids to potential leads

1 reference

12 December 2020

Reversible inhibition of the glycine transporter GlyT2 circumvents acute toxicity while preserving efficacy in the treatment of pain.

1 reference

12 December 2020

The discovery of potent glycine transporter type-2 inhibitors: design and synthesis of phenoxymethylbenzamide derivatives

1 reference

12 December 2020

Antinociceptive effect of intracerebroventricular administration of glycine transporter-2 inhibitor ALX1393 in rat models of inflammatory and neuropathic pain.

1 reference

12 December 2020

A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design.

1 reference

12 December 2020

Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain

1 reference

12 December 2020

The Unexpected Advantages of Using D-Amino Acids for Peptide Self- Assembly into Nanostructured Hydrogels for Medicine.

1 reference

12 December 2020

Glycinergic dysfunction in a subpopulation of dorsal horn interneurons in a rat model of neuropathic pain

1 reference

12 December 2020

Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2.

1 reference

12 December 2020

Modulation of Glycine-Mediated Spinal Neurotransmission for the Treatment of Chronic Pain.

1 reference

12 December 2020

Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2.

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12 December 2020

10.1021/ACS.JMEDCHEM.8B01775

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30714733%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

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21 April 2020

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