(Q64379354)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Simultaneous inhibition of Rac1 and IKK pathways sensitizes lung cancer cells to TNFalpha-mediated apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

S Sanlioglu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

G Luleci

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

K W Thomas

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

language of work or name

English

0 references

publication date

1 November 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

page(s)

897-905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700394

5 December 2019

exact match

0 references

cites work

Mechanisms of apoptosis

1 reference

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7 January 2021

Dicing with death: dissecting the components of the apoptosis machinery.

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7 January 2021

Life, death, and the pursuit of apoptosis.

1 reference

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7 January 2021

Apoptosis as a goal of cancer therapy

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7 January 2021

A new concept in neurodegeneration: TNFalpha is a silencer of survival signals

1 reference

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7 January 2021

RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

1 reference

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

TNF-alpha activates at least two apoptotic signaling cascades

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

NF-kappaB activation: the I kappaB kinase revealed?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Protection from reoxygenation injury by inhibition of rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

A simple method for the rapid generation of recombinant adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Expression of the cystic fibrosis gene in adult human lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Safety of airway gene transfer with Ad2/CFTR2: aerosol administration in the nonhuman primate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Recombinant E1-deleted adenovirus vector induces apoptosis in two lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Systematic analysis of repeated gene delivery into animal lungs with a recombinant adenovirus vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Coxsackievirus-adenovirus receptor expression in ovarian cancer cell lines is associated with increased adenovirus transduction efficiency and transgene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Regulation of the DNA binding activity of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Activation of nuclear transcription factor NF-kappaB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Rac1 regulates interleukin 1-induced nuclear factor kappaB activation in an inhibitory protein kappaBalpha-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700394

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700394

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11773980%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference