(Q64379651)

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Incorporation of 4-1BB ligand into an adenovirus vaccine vector increases the number of functional antigen-specific CD8 T cells and enhances the duration of protection against influenza-induced respiratory disease

scientific article published on 23 June 2011

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5 February 2020

Incorporation of 4-1BB ligand into an adenovirus vaccine vector increases the number of functional antigen-specific CD8 T cells and enhances the duration of protection against influenza-induced respiratory disease (English)

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5 February 2020

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respiratory disease

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Theo J Moraes

1

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5 February 2020

Gloria H Y Lin

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5 February 2020

Tao Wen

3

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5 February 2020

Tania H Watts

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5 February 2020

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5 February 2020

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5 February 2020

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5 February 2020

6301-6312

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5 February 2020

The influenza virus enigma

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Mortality associated with influenza and respiratory syncytial virus in the United States

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Preparing for the next influenza pandemic.

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Emergence and pandemic potential of swine-origin H1N1 influenza virus

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Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009

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Influenza and the challenge for immunology

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CD8 T cell responses to infectious pathogens.

1 reference

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7 January 2021

Declining T-cell immunity to influenza, 1977-82

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Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model

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7 January 2021

Cell-mediated protection in influenza infection.

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7 January 2021

Ab and T cell epitopes of influenza A virus, knowledge and opportunities

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7 January 2021

Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes

1 reference

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7 January 2021

Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein.

1 reference

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7 January 2021

Heterologous protection against influenza by injection of DNA encoding a viral protein

1 reference

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7 January 2021

Partial protection against H5N1 influenza in mice with a single dose of a chimpanzee adenovirus vector expressing nucleoprotein

1 reference

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7 January 2021

Efficacy of influenza haemagglutinin and nucleoprotein as protective antigens against influenza virus infection in mice

1 reference

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7 January 2021

Characterization and Immunological Properties of Influenza A Virus Nucleoprotein (NP): Cell-associated NP Isolated from Infected Cells or Viral NP Expressed by Vaccinia Recombinant Virus do not Confer Protection

1 reference

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7 January 2021

New insights on adenovirus as vaccine vectors

1 reference

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7 January 2021

Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors

1 reference

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7 January 2021

Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

1 reference

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7 January 2021

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

1 reference

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7 January 2021

Expression characteristics of two potential T cell mediator genes

1 reference

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7 January 2021

Immune regulation by 4-1BB and 4-1BBL: complexities and challenges

1 reference

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7 January 2021

TNF/TNFR family members in costimulation of T cell responses

1 reference

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7 January 2021

Immune responses in 4-1BB (CD137)-deficient mice

1 reference

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7 January 2021

Influenza virus

1 reference

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7 January 2021

Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease

1 reference

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7 January 2021

Adenoviral vectors for mucosal vaccination against infectious diseases.

1 reference

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7 January 2021

A broadly protective vaccine against globally dispersed clade 1 and clade 2 H5N1 influenza viruses.

1 reference

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7 January 2021

Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1 reference

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7 January 2021

Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications

1 reference

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7 January 2021

Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus

1 reference

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7 January 2021

Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human

1 reference

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7 January 2021

4-1BB functions as a survival factor in dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

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7 January 2021

Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice

1 reference

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Cellular response to respiratory viruses with particular reference to children with disorders of cell-mediated immunity

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Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccine

1 reference

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7 January 2021

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

1 reference

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7 January 2021

Shaping and reshaping CD8+ T-cell memory.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival.

1 reference

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7 January 2021

Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses

1 reference

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7 January 2021

Mucosal immunity and protection after intranasal immunization with recombinant adenovirus expressing herpes simplex virus glycoprotein B.

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7 January 2021

Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization

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7 January 2021

What role does the route of immunization play in the generation of protective immunity against mucosal pathogens?

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Opportunities and challenges of the pulmonary route for vaccination

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Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis

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Pulmonary mucosal dendritic cells in T-cell activation: implications for TB therapy

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4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells

1 reference

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Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice

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Profound protection against respiratory challenge with a lethal H7N7 influenza A virus by increasing the magnitude of CD8(+) T-cell memory

1 reference

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7 January 2021

A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.

1 reference

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7 January 2021

Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice

1 reference

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7 January 2021

Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization

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7 January 2021

Multi-antigen vaccines based on complex adenovirus vectors induce protective immune responses against H5N1 avian influenza viruses.

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Comparison of vaccines for induction of heterosubtypic immunity to influenza A virus: cold-adapted vaccine versus DNA prime-adenovirus boost strategies

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New pre-pandemic influenza vaccines: an egg- and adjuvant-independent human adenoviral vector strategy induces long-lasting protective immune responses in mice.

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The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer

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Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge

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7 January 2021

based on heuristic

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Effects of low- and high-passage influenza virus infection in normal and nude mice

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.06.022

7 January 2021

based on heuristic

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10.1016/J.VACCINE.2011.06.022

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21704101%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21704101%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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