(Q64388386)

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Heterogenous fusion transcripts involving the NUP98 gene and HOXD13 gene activation in a case of acute myeloid leukemia with the t(2;11)(q31;p15) translocation

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995009%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Heterogenous fusion transcripts involving the NUP98 gene and HOXD13 gene activation in a case of acute myeloid leukemia with the t(2;11)(q31;p15) translocation (English)

1 reference

Europe PubMed Central

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10 November 2019

1 reference

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acute myeloid leukemia

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author name string

Y Arai

1

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10 November 2019

T Kyo

2

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10 November 2019

H Miwa

3

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10 November 2019

K Arai

4

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10 November 2019

N Kamada

5

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10 November 2019

K Kita

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10 November 2019

M Ohki

7

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10 November 2019

language of work or name

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1 September 2000

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10 November 2019

1 reference

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10 November 2019

14

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10 November 2019

1621-1629

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10 November 2019

9

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10 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2401881

0 references

Chromosomal translocations in human cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleocytoplasmic transport: the last 200 nanometers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

11p15 translocations involving the NUP98 gene in childhood therapy-related acute myeloid leukemia/myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Hox homeobox genes as regulators of normal and leukemic hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification of CpG islands using a methylated DNA binding column

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

A common mechanism of chromosomal translocation in T- and B-cell neoplasia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

AML1 fusion transcripts in t(3;21) positive leukemia: evidence of molecular heterogeneity and usage of splicing sites frequently involved in the generation of normal AML1 transcripts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic structure of HOXD13 gene: a nine polyalanine duplication causes synpolydactyly in two unrelated families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel gene, Translin, encodes a recombination hotspot binding protein associated with chromosomal translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401881

7 January 2021

based on heuristic

inferred from DOI database lookup

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