(Q647813)

Protein-glutamine gamma-glutamyltransferase, animal

1 reference

Immunoglobulin-like fold

1 reference

Transglutaminase, C-terminal domain superfamily

1 reference

Immunoglobulin E-set

1 reference

Papain-like cysteine peptidase superfamily

1 reference

Transglutaminase, N-terminal domain, protein family

1 reference

Transglutaminase-like family

1 reference

Transglutaminase, C-terminal domain, protein family

1 reference

Transglutaminase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

acyltransferase activity

1 reference

9 May 2019

protein-glutamine gamma-glutamyltransferase activity

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

8 April 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

10 references

9 May 2019

Identification of the eukaryotic initiation factor 5A as a retinoic acid-stimulated cellular binding partner for tissue transglutaminase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

The first draft of the endostatin interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Tissue transglutaminase interacts with protein kinase A anchor protein 13 in prostate cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Cancer cells promote survival through depletion of the von Hippel-Lindau tumor suppressor by protein crosslinking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

The Multimerization State of the Amyloid-β42 Amyloid Peptide Governs its Interaction Network with the Extracellular Matrix

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

protein domain specific binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

protein-glutamine gamma-glutamyltransferase activity

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

intrinsic component of plasma membrane

2 references

1 reference

9 May 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21980&geneProductId=UniProtKB:P21980

IDA

endoplasmic reticulum

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

1 reference

17 October 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21980&geneProductId=UniProtKB:P21980

1 reference

9 May 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

collagen-containing extracellular matrix

HDA

4 references

9 May 2019

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

Induction of transglutaminase 2 by a liver X receptor/retinoic acid receptor alpha pathway increases the clearance of apoptotic cells by human macrophages

IBA

biological process

apoptotic cell clearance

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

phospholipase C-activating G protein-coupled receptor signaling pathway

IDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

salivary gland cavitation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

peptide cross-linking

1 reference

8 April 2019

branching involved in salivary gland morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

positive regulation of inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

protein homooligomerization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

positive regulation of smooth muscle cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

blood vessel remodeling

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21980

http://purl.uniprot.org/uniprot/P21980

Gene Atlas image

PBB GE TGM2 201042 at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

D08.811.913.050.200.800.650

Identifiers.org

Identifiers

MeSH descriptor ID

D000091345

subject named as

Protein Glutamine gamma Glutamyltransferase 2

0 references

MeSH tree code

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

28 October 2013

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference