(Q6481869)

http://www.ebi.ac.uk/interpro/protein/Q14739

Tudor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sterol reductase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Lamin-B receptor of TUDOR domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

2 references

13 November 2019

17 September 2016

2 references

13 November 2019

30 June 2016

language of work or name

English

molecular function

oxidoreductase activity, acting on the CH-CH group of donors

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

chromo shadow domain binding

1 reference

8 April 2019

The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

1 reference

8 April 2019

Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

delta14-sterol reductase activity

TAS

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

1 reference

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

1 reference

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

delta14-sterol reductase activity

HDA

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Autosomal recessive HEM/Greenberg skeletal dysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutations in the lamin B receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Human lamin B receptor exhibits sterol C14-reductase activity in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

1 reference

8 April 2019

The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

IMP

oxidoreductase activity

1 reference

8 April 2019

integral component of endoplasmic reticulum membrane

cell component

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

IBA

nuclear inner membrane

1 reference

26 September 2017

integral component of nuclear inner membrane

1 reference

8 April 2019

Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

1 reference

14 January 2019

Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

endoplasmic reticulum membrane

IDA

1 reference

14 January 2019

Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

endoplasmic reticulum

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

cholesterol biosynthetic process

biological process

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

sterol biosynthetic process

TAS

1 reference

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14739&geneProductId=UniProtKB:Q14739

cholesterol biosynthetic process

IBA

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

8 April 2019

Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

steroid biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

steroid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739

cholesterol metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14739