(Q64898209)

30 June 2019

title

Amino acid substitutions in the human genome: evolutionary implications of single nucleotide polymorphisms. (English)

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30 June 2019

author name string

Jacek Majewski

series ordinal

1

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30 June 2019

Jurg Ott

series ordinal

2

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30 June 2019

language of work or name

English

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publication date

1 February 2003

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30 June 2019

published in

Gene

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30 June 2019

volume

305

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30 June 2019

issue

2

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30 June 2019

page(s)

167-173

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30 June 2019

Selective Constraints on Amino-acid Substitutions during the Evolution of Proteins

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Site-directed mutagenesis implicates a threonine residue in TM6 in the subtype selectivities of UH-AH 37 and pirenzepine at muscarinic receptors.

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Amino acid difference formula to help explain protein evolution

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Wide variations in neighbor-dependent substitution rates.

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A Structural Basis for Sequence Comparisons

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A mutation data matrix for transmembrane proteins

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The rate of molecular evolution considered from the standpoint of population genetics

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Neighboring-nucleotide effects on the rates of germ-line single-base-pair substitution in human genes

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Nonrandomness of point mutation as reflected in nucleotide substitutions in pseudogenes and its evolutionary implications

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Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity

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Repeating sequences and gene duplication in proteins

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Two types of amino acid substitutions in protein evolution

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A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

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Relations between chemical structure and biological activity in peptides

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A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation

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What amino acid properties affect protein evolution?

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10.1016/S0378-1119(03)00379-2

Identifiers

DOI

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30 June 2019

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30 June 2019