(Q64914366)

30 June 2019

title

Desmoplasia in pancreatic ductal adenocarcinoma: insight into pathological function and therapeutic potential. (English)

1 reference

30 June 2019

invasive ductal carcinoma

main subject

1 reference

pancreatic ductal adenocarcinoma

inferred from title

1 reference

pancreatic ductal carcinoma

inferred from title

1 reference

Andrew Cannon

1

1 reference

30 June 2019

Christopher Thompson

2

1 reference

30 June 2019

Bradley R Hall

3

1 reference

30 June 2019

Maneesh Jain

4

1 reference

30 June 2019

Sushil Kumar

5

1 reference

30 June 2019

Surinder K Batra

6

1 reference

30 June 2019

publication date

1 March 2018

1 reference

30 June 2019

published in

Genes & Cancer

1 reference

30 June 2019

volume

9

1 reference

30 June 2019

issue

3-4

1 reference

30 June 2019

page(s)

78-86

1 reference

30 June 2019

Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma

cites work

1 reference

12 December 2020

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

1 reference

12 December 2020

Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma.

1 reference

12 December 2020

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

1 reference

12 December 2020

Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells

1 reference

12 December 2020

Pancreatic stellate cells: partners in crime with pancreatic cancer cells

1 reference

12 December 2020

Hedgehog signaling is required for effective regeneration of exocrine pancreas

1 reference

12 December 2020

Sonic hedgehog promotes desmoplasia in pancreatic cancer

1 reference

12 December 2020

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

1 reference

12 December 2020

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

12 December 2020

Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia

1 reference

12 December 2020

Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts

1 reference

12 December 2020

Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells

1 reference

12 December 2020

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

1 reference

12 December 2020

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

1 reference

12 December 2020

Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells

1 reference

12 December 2020

Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor

1 reference

12 December 2020

The angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice

1 reference

12 December 2020

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner

1 reference

12 December 2020

A starring role for stellate cells in the pancreatic cancer microenvironment

1 reference

12 December 2020

Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer

1 reference

12 December 2020

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

1 reference

12 December 2020

Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer

1 reference

12 December 2020

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

1 reference

12 December 2020

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

1 reference

12 December 2020

Stromal response to Hedgehog signaling restrains pancreatic cancer progression

1 reference

12 December 2020

Fibroblast heterogeneity in the cancer wound

1 reference

12 December 2020

The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling

1 reference

12 December 2020

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

1 reference

12 December 2020

Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma

1 reference

12 December 2020

Dosage-dependent regulation of pancreatic cancer growth and angiogenesis by hedgehog signaling

1 reference

12 December 2020

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

1 reference

12 December 2020

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

1 reference

12 December 2020

A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma

1 reference

12 December 2020

Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer

1 reference

12 December 2020

The role of hypoxia in pancreatic cancer: a potential therapeutic target?

1 reference

12 December 2020

Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

1 reference

12 December 2020

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

1 reference

12 December 2020

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

1 reference

12 December 2020

Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

1 reference

12 December 2020

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

1 reference

12 December 2020

Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

1 reference

12 December 2020

HALO 202: Randomized Phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal Adenocarcinoma.

1 reference

12 December 2020

Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition

1 reference

12 December 2020

Cancer statistics, 2018.

1 reference

12 December 2020

Advanced pancreatic cancer: a meta-analysis of clinical trials over thirty years.

1 reference

12 December 2020

10.18632/GENESANDCANCER.171

Identifiers

DOI

1 reference

30 June 2019

PMCID

6086006

1 reference

30 June 2019

PubMed ID

30108679

1 reference

30 June 2019