(Q64916381)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

title

The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

main subject

endoplasmic reticulum

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Greg J Poet

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

author name string

Kristine Faye R Pobre

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

language of work or name

English

0 references

publication date

18 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

15 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

volume

294

1 reference

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15 April 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

page(s)

2098-2108

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

15 April 2020

cites work

1 reference

12 December 2020

Interconversion of three differentially modified and assembled forms of BiP

1 reference

12 December 2020

Endocytosis of simian virus 40 into the endoplasmic reticulum

1 reference

12 December 2020

Identity of the immunoglobulin heavy-chain-binding protein with the 78,000-dalton glucose-regulated protein and the role of posttranslational modifications in its binding function

1 reference

12 December 2020

ADP-ribosylation of the Mr 83,000 stress-inducible and glucose-regulated protein in avian and mammalian cells: modulation by heat shock and glucose starvation

1 reference

12 December 2020

The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

1 reference

12 December 2020

In Vitro Dissociation of BiP-Peptide Complexes Requires a Conformational Change in BiP after ATP Binding but Does Not Require ATP Hydrolysis

1 reference

12 December 2020

Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.

1 reference

12 December 2020

The role of the thiol/disulfide centers and peptide binding site in the chaperone and anti-chaperone activities of protein disulfide isomerase

1 reference

12 December 2020

A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome

1 reference

12 December 2020

The 58-kDa cellular inhibitor of the double stranded RNA-dependent protein kinase requires the tetratricopeptide repeat 6 and DnaJ motifs to stimulate protein synthesis in vivo

1 reference

12 December 2020

Structure, function and evolution of DnaJ: conservation and adaptation of chaperone function

1 reference

12 December 2020

J proteins catalytically activate Hsp70 molecules to trap a wide range of peptide sequences

1 reference

12 December 2020

HEDJ, an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells

1 reference

12 December 2020

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

1 reference

12 December 2020

Sec62p, a component of the endoplasmic reticulum protein translocation machinery, contains multiple binding sites for the Sec-complex

1 reference

12 December 2020

Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone.

1 reference

12 December 2020

Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

1 reference

12 December 2020

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

1 reference

12 December 2020

Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release

1 reference

12 December 2020

Upregulation of the cochaperone Mdg1 in endothelial cells is induced by stress and during in vitro angiogenesis

1 reference

12 December 2020

Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress

1 reference

12 December 2020

ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress

1 reference

12 December 2020

JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs

1 reference

12 December 2020

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

1 reference

12 December 2020

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins

1 reference

12 December 2020

Quality control in the endoplasmic reticulum

1 reference

12 December 2020

Calcium signalling: dynamics, homeostasis and remodelling

1 reference

12 December 2020

High levels of the molecular chaperone Mdg1/ERdj4 reflect the activation state of endothelial cells.

1 reference

12 December 2020

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

1 reference

12 December 2020

The crystal structure of the yeast Hsp40 Ydj1 complexed with its peptide substrate

1 reference

12 December 2020

Ca2+-dependent redox modulation of SERCA 2b by ERp57.

1 reference

12 December 2020

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

1 reference

12 December 2020

ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates

1 reference

12 December 2020

The human protein disulphide isomerase family: substrate interactions and functional properties

1 reference

12 December 2020

The crystal structure of the C-terminal fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40.

1 reference

12 December 2020

ERj1p uses a universal ribosomal adaptor site to coordinate the 80S ribosome at the membrane.

1 reference

12 December 2020

ERj1p has a basic role in protein biogenesis at the endoplasmic reticulum

1 reference

12 December 2020

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

1 reference

12 December 2020

The role of p58IPK in protecting the stressed endoplasmic reticulum

1 reference

12 December 2020

The heat shock protein 70 molecular chaperone network in the pancreatic endoplasmic reticulum - a quantitative approach

1 reference

12 December 2020

Contribution of the HEDJ/ERdj3 cysteine-rich domain to substrate interactions.

1 reference

12 December 2020

ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C

1 reference

12 December 2020

ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER

1 reference

12 December 2020

Regulated release of ERdj3 from unfolded proteins by BiP

1 reference

12 December 2020

Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3

1 reference

12 December 2020

ERdj3, a luminal ER DnaJ homologue, binds directly to unfolded proteins in the mammalian ER: identification of critical residues

1 reference

12 December 2020

An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.

1 reference

12 December 2020

Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7.

1 reference

12 December 2020

Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland

1 reference

12 December 2020

The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones

1 reference

12 December 2020

Organization of the Sec61 translocon, studied by high resolution native electrophoresis.

1 reference

12 December 2020

Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPR

1 reference

12 December 2020

Comparing the functional properties of the Hsp70 chaperones, DnaK and BiP.

1 reference

12 December 2020

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

1 reference

12 December 2020

BiP modulates the affinity of its co-chaperone ERj1 for ribosomes

1 reference

12 December 2020

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions.

1 reference

12 December 2020

Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5

1 reference

12 December 2020

Protein folding and modification in the mammalian endoplasmic reticulum.

1 reference

12 December 2020

The Crystal Structure of the Human Co-Chaperone P58IPK

1 reference

12 December 2020

ERdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machinery

1 reference

12 December 2020

Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells

1 reference

12 December 2020

Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones

1 reference

12 December 2020

Structural characterization of a eukaryotic chaperone--the ribosome-associated complex

1 reference

12 December 2020

An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones

1 reference

12 December 2020

The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation

1 reference

12 December 2020

ERdj3 regulates BiP occupancy in living cells

1 reference

12 December 2020

Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP

1 reference

12 December 2020

ERdj5 is the ER reductase that catalyzes the removal of non-native disulfides and correct folding of the LDL receptor

1 reference

12 December 2020

Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects

1 reference

12 December 2020

Emerging features of ER resident J-proteins in plants

1 reference

12 December 2020

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

1 reference

12 December 2020

The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control

1 reference

12 December 2020

ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.

1 reference

12 December 2020

Dissection of structural and functional requirements that underlie the interaction of ERdj3 protein with substrates in the endoplasmic reticulum

1 reference

12 December 2020

The BiP cochaperone ERdj4 is required for B cell development and function

1 reference

12 December 2020

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

1 reference

12 December 2020

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.

1 reference

12 December 2020

Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis.

1 reference

12 December 2020

A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response

1 reference

12 December 2020

BiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functions

1 reference

12 December 2020

Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity

1 reference

12 December 2020

ERdj5 Reductase Cooperates with Protein Disulfide Isomerase To Promote Simian Virus 40 Endoplasmic Reticulum Membrane Translocation

1 reference

12 December 2020

A bacterial toxin and a nonenveloped virus hijack ER-to-cytosol membrane translocation pathways to cause disease

1 reference

12 December 2020

Insights into the molecular mechanism of allostery in Hsp70s

1 reference

12 December 2020

Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP

1 reference

12 December 2020

AMPylation matches BiP activity to client protein load in the endoplasmic reticulum

1 reference

12 December 2020

Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs

1 reference

12 December 2020

Members of the Hsp70 Family Recognize Distinct Types of Sequences to Execute ER Quality Control.

1 reference

12 December 2020

Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5.

1 reference

12 December 2020

FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP.

1 reference

12 December 2020

Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation

1 reference

12 December 2020

The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation

1 reference

12 December 2020

The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.

1 reference

12 December 2020

AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.

1 reference

12 December 2020

Allosteric fine-tuning of the conformational equilibrium poises the chaperone BiP for post-translational regulation

1 reference

12 December 2020

Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s

1 reference

12 December 2020

How Are Proteins Reduced in the Endoplasmic Reticulum?

1 reference

12 December 2020

A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

1 reference

12 December 2020

Molecular Mechanism of J-Domain-Triggered ATP Hydrolysis by Hsp70 Chaperones

1 reference

12 December 2020

Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier.

1 reference

12 December 2020

Intra-molecular pathways of allosteric control in Hsp70s

1 reference

12 December 2020

10.1074/JBC.REV118.002804

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563838%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

30563838

1 reference