(Q64935880)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29856956%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia (English)

1 reference

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29 March 2020

1 reference

2

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29 March 2020

Katherine Cummins

12

1 reference

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29 March 2020

author name string

Miriam Y Kim

1

1 reference

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29 March 2020

Saad S Kenderian

3

1 reference

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29 March 2020

Marco Ruella

4

1 reference

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29 March 2020

Shirley Chen

5

1 reference

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29 March 2020

Tae-Hoon Shin

6

1 reference

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29 March 2020

Aisha A Aljanahi

7

1 reference

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29 March 2020

Daniel Schreeder

8

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29 March 2020

Michael Klichinsky

9

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29 March 2020

Olga Shestova

10

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29 March 2020

Miroslaw S Kozlowski

11

1 reference

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29 March 2020

Xinhe Shan

13

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29 March 2020

Maksim Shestov

14

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29 March 2020

Adam Bagg

15

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29 March 2020

Jennifer J D Morrissette

16

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29 March 2020

Palak Sekhri

17

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29 March 2020

Cicera R Lazzarotto

18

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29 March 2020

Katherine R Calvo

19

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29 March 2020

Douglas B Kuhns

20

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29 March 2020

Robert E Donahue

21

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29 March 2020

Gregory K Behbehani

22

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29 March 2020

Shengdar Q Tsai

23

1 reference

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29 March 2020

Cynthia E Dunbar

24

1 reference

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29 March 2020

Saar Gill

25

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29 March 2020

language of work or name

English

0 references

publication date

31 May 2018

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29 March 2020

1 reference

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29 March 2020

volume

173

1 reference

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29 March 2020

issue

6

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29 March 2020

page(s)

1439-1453.e19

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describes a project that uses

29 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6003425/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2

1 reference

12 December 2020

The sialoadhesin CD33 is a myeloid-specific inhibitory receptor

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Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

1 reference

12 December 2020

CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice

1 reference

12 December 2020

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

1 reference

12 December 2020

Myeloid precursors and acute myeloid leukemia cells express multiple CD33-related Siglecs

1 reference

12 December 2020

Large animal models for stem and progenitor cell analysis

1 reference

12 December 2020

Development of analytical methods for multiplex bio-assay with inductively coupled plasma mass spectrometry

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

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12 December 2020

Web-based analysis and publication of flow cytometry experiments

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12 December 2020

Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?

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12 December 2020

Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment.

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12 December 2020

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

1 reference

12 December 2020

In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia

1 reference

12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

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12 December 2020

Normalization of mass cytometry data with bead standards

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12 December 2020

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

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12 December 2020

Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo.

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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

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Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells

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Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells

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The past and future of CD33 as therapeutic target in acute myeloid leukemia.

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12 December 2020

Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33

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12 December 2020

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

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12 December 2020

Treatment of CD33-directed chimeric antigen receptor-modified T cells in one patient with relapsed and refractory acute myeloid leukemia

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12 December 2020

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12 December 2020

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

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12 December 2020

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells

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12 December 2020

CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia

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12 December 2020

Identification of a large set of rare complete human knockouts

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12 December 2020

Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy

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Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

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Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

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In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

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12 December 2020

10.1016/J.CELL.2018.05.013

Identifiers

DOI

1 reference

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29 March 2020

1 reference

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29 March 2020

PubMed publication ID

29856956

1 reference