(Q64979026)

2 July 2019

title

TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. (English)

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2 July 2019

author

Paul A Overbeek

8

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2 July 2019

author name string

D Zhang

1

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2 July 2019

V Gaussin

2

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2 July 2019

G E Taffet

3

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2 July 2019

N S Belaguli

4

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2 July 2019

M Yamada

5

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2 July 2019

R J Schwartz

6

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2 July 2019

L H Michael

7

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M D Schneider

9

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2 July 2019

language of work or name

English

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publication date

1 May 2000

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2 July 2019

published in

Nature Medicine

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2 July 2019

volume

6

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2 July 2019

page(s)

556-563

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2 July 2019

issue

5

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2 July 2019

https://scigraph.springernature.com/pub.10.1038/75037

exact match

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cites work

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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

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7 January 2021

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p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6.

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7 January 2021

Avian serum response factor expression restricted primarily to muscle cell lineages is required for alpha-actin gene transcription.

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7 January 2021

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

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Interaction of ATF6 and serum response factor

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7 January 2021

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

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7 January 2021

Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components

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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

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Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes

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A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice.

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Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

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7 January 2021

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7 January 2021

Human E2F-1 reactivates cell cycle progression in ventricular myocytes and represses cardiac gene transcription

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7 January 2021

Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy

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7 January 2021

Identification of a transforming growth factor-beta1/bone morphogenetic protein 4 (TGF-beta1/BMP4) response element within the mouse tissue transglutaminase gene promoter

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7 January 2021

Identifiers

DOI

10.1038/75037

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2 July 2019

PubMed ID

10802712

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2 July 2019