(Q64983297)

2 July 2019

title

Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase. (English)

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2 July 2019

author name string

Shengjun Wang

1

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2 July 2019

Wenjie Zhu

2

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2 July 2019

Xuan Wang

3

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2 July 2019

Jianguo Li

4

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2 July 2019

Kehui Zhang

5

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2 July 2019

Liangren Zhang

6

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2 July 2019

Yong-Juan Zhao

7

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2 July 2019

Hon Cheung Lee

8

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2 July 2019

Lihe Zhang

9

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2 July 2019

language of work or name

English

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publication date

29 September 2014

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2 July 2019

published in

Molecules

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2 July 2019

volume

19

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2 July 2019

issue

10

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2 July 2019

page(s)

15754-15767

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2 July 2019

Creative Commons Attribution 4.0 International

copyright license

start time

29 September 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

12 December 2020

Bacterial DNA ligases.

1 reference

12 December 2020

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

1 reference

12 December 2020

NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs

1 reference

12 December 2020

Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis

1 reference

12 December 2020

NAD+ metabolism in health and disease

1 reference

12 December 2020

Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38

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12 December 2020

CD38 is critical for social behaviour by regulating oxytocin secretion.

1 reference

12 December 2020

Nicotinamide adenine dinucleotide: beyond a redox coenzyme

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12 December 2020

Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38

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12 December 2020

Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose

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12 December 2020

TRPM2: a multifunctional ion channel for calcium signalling.

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12 December 2020

Stereoselective synthesis of PSI-352938: a β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV.

1 reference

12 December 2020

Catalysis-based inhibitors of the calcium signaling function of CD38

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12 December 2020

Design, synthesis and biological evaluation of noncovalent inhibitors of human CD38 NADase

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12 December 2020

Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists

1 reference

12 December 2020

Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe.

1 reference

12 December 2020

Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.

1 reference

12 December 2020

Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

1 reference

12 December 2020

Human CD38 is an authentic NAD(P)+ glycohydrolase

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12 December 2020

The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries

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12 December 2020

CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion

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12 December 2020

10.3390/MOLECULES191015754

Identifiers

DOI

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2 July 2019

PMC publication ID

6271716

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2 July 2019

PubMed publication ID

25268725

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2 July 2019