(Q6714930)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49736

DNA replication licensing factor Mcm2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49736

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49736

MCM N-terminal domain, protein family

1 reference

MCM OB domain, protein family

1 reference

MCM domain, protein family

1 reference

Mini-chromosome maintenance, conserved site, protein family

1 reference

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

1 reference

13 November 2019

1 reference

13 November 2019

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49736&geneProductId=UniProtKB:P49736

DNA helicase activity

1 reference

31 October 2017

22 references

9 May 2019

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Analysis of interaction partners of H4 histone by a new proteomics approach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Protein Kinase A-anchoring Protein AKAP95 Interacts with MCM2, a Regulator of DNA Replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Identification and characterization of a novel component of the human minichromosome maintenance complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Self-assembling protein microarrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Interaction of chromatin-associated Plk1 and Mcm7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

The interaction between EAP30 and ELL is modulated by MCM2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Interactions of the human MCM-BP protein with MCM complex components and Dbf4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

DNA replication origin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

single-stranded DNA binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

single-stranded DNA helicase activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

3'-5' DNA helicase activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

IDA

microtubule cytoskeleton

1 reference

9 May 2019

nuclear origin of replication recognition complex

IDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

6 references

8 April 2019

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

8 April 2019

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

8 April 2019

Interactions of MCP1 with components of the replication machinery in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49736&geneProductId=UniProtKB:P49736

1 reference

9 May 2019

Interactions of MCP1 with components of the replication machinery in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

7 references

9 May 2019

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Interactions of MCP1 with components of the replication machinery in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Identification and characterization of a novel component of the human minichromosome maintenance complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

cellular response to interleukin-4

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49736&geneProductId=UniProtKB:P49736

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

DNA unwinding involved in DNA replication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

1 reference

9 May 2019

Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

G1/S transition of mitotic cell cycle

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

negative regulation of DNA helicase activity

TAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

double-strand break repair via break-induced replication

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

pre-replicative complex assembly involved in nuclear cell cycle DNA replication

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

mitotic DNA replication initiation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49736

D08.811.277.040.025.159.186.200

Gene Atlas image

PBB GE MCM2 202107 s at fs.png
732 × 530; 11 KB

0 references

Identifiers

MeSH descriptor ID

D064111

subject named as

Minichromosome Maintenance Complex Component 2

0 references

MeSH tree code

0 references

D08.811.399.340.186.200

0 references

D12.776.167.409.200

0 references

D12.776.660.235.500.200

0 references

D12.776.664.235.750.200

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference