(Q67487325)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

5 references

20 November 2019

27 November 2019

26 October 2020

8 February 2021

24 January 2024

Insulin-like growth factors and cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

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20 November 2019

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27 November 2019

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26 October 2020

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8 February 2021

V M Macaulay

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

language of work or name

English

0 references

publication date

1 March 1992

6 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

20 November 2019

27 November 2019

26 October 2020

8 February 2021

24 January 2024

British Journal of Cancer

6 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

20 November 2019

27 November 2019

26 October 2020

8 February 2021

24 January 2024

65

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

page(s)

311-320

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/bjc.1992.65

14 September 2019

exact match

0 references

cites work

Expression of two insulin-like growth factor-binding proteins in a human endometrial cancer cell line: structural, immunological, and genetic characterization

1 reference

12 December 2020

Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor

1 reference

12 December 2020

Signal transmission by the insulin-like growth factors

1 reference

12 December 2020

Human teratocarcinoma cells express functional insulin-like growth factor I receptors.

1 reference

12 December 2020

Antibody to type I insulinlike growth factor receptor inhibits growth of Wilms' tumor in culture and in athymic mice

1 reference

12 December 2020

Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates

1 reference

12 December 2020

Functional receptors for insulin-like growth factors I and II in rat thymocytes and mouse thymoma cells

1 reference

12 December 2020

Insulin-like growth factor II and the riddle of tumor-induced hypoglycemia

1 reference

12 December 2020

Insulin-like growth factor I receptors in normal and neoplastic human endometrium

1 reference

12 December 2020

Production of immunoreactive insulin-like growth factor I and response to exogenous IGF-I in small cell lung cancer cell lines

1 reference

12 December 2020

Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro

1 reference

12 December 2020

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

1 reference

12 December 2020

SMS 201-995 induces a continuous decline in circulating growth hormone and somatomedin-C levels during therapy of acromegalic patients for over two years

1 reference

12 December 2020

Effect of tamoxifen on plasma insulin-like growth factor I in patients with breast cancer.

1 reference

12 December 2020

Insulin-like growth factor II receptor as a multifunctional binding protein

1 reference

12 December 2020

An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture

1 reference

12 December 2020

The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells

1 reference

12 December 2020

Insulin-like growth factors and the multiplication of Tera-2, a human teratoma-derived cell line.

1 reference

12 December 2020

Somatomedin C/insulin-like growth factor I production by human fetal lung tissue maintained in vitro

1 reference

12 December 2020

Insulin-like growth factors/somatomedins: structure, secretion, biological actions and physiological role

1 reference

12 December 2020

Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus

1 reference

12 December 2020

Autocrine tumour growth regulation by somatomedin C: an in-vitro model

1 reference

12 December 2020

Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells

1 reference

12 December 2020

Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas

1 reference

12 December 2020

Relative increase in insulin-like growth factor I messenger ribonucleic acid levels in compensatory renal hypertrophy

1 reference

12 December 2020

Evidence for an increased somatomedin-C/insulin-like growth factor I content in primary human lung tumors

1 reference

12 December 2020

A partially purified polypeptide fraction from rat liver cell conditioned medium with multiplication-stimulating activity for embryo fibroblasts

1 reference

12 December 2020

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor

1 reference

12 December 2020

Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture

1 reference

12 December 2020

Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C

1 reference

12 December 2020

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action

1 reference

12 December 2020

Is extrapancreatic tumor hypoglycemia associated with elevated levels of insulin-like growth factor II?

1 reference

12 December 2020

Somatomedin-C and platelet-derived growth factor stimulate human fibroblast replication

1 reference

12 December 2020

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

1 reference

12 December 2020

ANTIBODY-SUPPRESSIBLE AND NONSUPPRESSIBLE INSULIN-LIKE ACTIVITIES IN HUMAN SERUM AND THEIR PHYSIOLOGIC SIGNIFICANCE. AN INSULIN ASSAY WITH ADIPOSE TISSUE OF INCREASED PRECISION AND SPECIFICITY

1 reference

12 December 2020

Primary structure of human insulin-like growth factor II.

1 reference

12 December 2020

Opposite imprinting of the mouse Igf2 and Igf2r genes

1 reference

12 December 2020

Uniparental paternal disomy in a genetic cancer-predisposing syndrome

1 reference

12 December 2020

Autocrine Regulation of Human Tumor Cell Proliferation by Insulin-Like Growth Factor II: anin-VitroModel*

1 reference

12 December 2020

Dads and disomy and disease

1 reference

12 December 2020

Insulin-like growth factor I and transforming growth factor alpha as autocrine growth factors in human pancreatic cancer cell growth

1 reference

12 December 2020

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

1 reference

12 December 2020

Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells

1 reference

12 December 2020

The possible autocrine/paracrine and endocrine roles of insulin-like growth factors of human tumors

1 reference

12 December 2020

Abnormal processing of pro-IGF-II in patients with hepatoma and in some hepatitis B virus antibody-positive asymptomatic individuals

1 reference

12 December 2020

Insulin-like growth factors I and II.

1 reference

12 December 2020

Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients

1 reference

12 December 2020

Multihormonal regulation of the progesterone receptor in MCF-7 human breast cancer cells: interrelationships among insulin/insulin-like growth factor-I, serum, and estrogen

1 reference

12 December 2020

Treatment of the malignant carcinoid syndrome. Evaluation of a long-acting somatostatin analogue

1 reference

12 December 2020

Insulin-like growth factor (IGF) binding protein from human decidua inhibits the binding and biological action of IGF-I in cultured choriocarcinoma cells.

1 reference

12 December 2020

On the nomenclature of the somatomedins and insulin-like growth factors.

1 reference

12 December 2020

Estrogen-induced factors of breast cancer cells partially replace estrogen to promote tumor growth

1 reference

12 December 2020

Biosynthetic somatomedin C (SM-C/IGF-I) increases the length and weight of Snell dwarf mice.

1 reference

12 December 2020

Insulin-like growth factors and insulin: comparative aspects

1 reference

12 December 2020

The partial purification from calf serum of a fraction with multiplication-stimulating activity for chicken fibroblasts in cell culture and with non-suppressible insulin-like activity

1 reference

12 December 2020

Monoclonal antibodies to receptors for insulin and somatomedin-C

1 reference

12 December 2020

Sequence analysis of somatomedin-C: confirmation of identity with insulin-like growth factor I

1 reference

12 December 2020

Production of an insulin-like growth factor by osteosarcoma

1 reference

12 December 2020

Purification and primary structure of a polypeptide with multiplication-stimulating activity from rat liver cell cultures. Homology with human insulin-like growth factor II

1 reference

12 December 2020

Autocrine secretion and malignant transformation of cells.

1 reference

12 December 2020

FAMILIAL MALFORMATION COMPLEX WITH UMBILICAL HERNIA AND MACROGLOSSIA--A "NEW SYNDROME"?

1 reference

12 December 2020

Serum half-life and biological activity of mutants of human insulin-like growth factor I which do not bind to serum binding proteins

1 reference

12 December 2020

Insulin-like growth factor (IGF) binding protein complementary deoxyribonucleic acid from human HEP G2 hepatoma cells: predicted protein sequence suggests an IGF binding domain different from those of the IGF-I and IGF-II receptors

1 reference

12 December 2020

Somatomedin-C/insulinlike growth factor I (Sm-C/IGF-I) and insulinlike growth factor II (IGF-II) mRNAs during lung development in the rat.

1 reference

12 December 2020

Characterization of insulin-like growth factor binding proteins from human breast cancer cells

1 reference

12 December 2020

Insulin-like growth factors; autocrine, paracrine or endocrine? New perspectives of the somatomedin hypothesis in the light of recent developments

1 reference

12 December 2020

Immunoreactive insulin-like growth factor I (IGF-I) and IGF-I-binding protein content in human thyroid tissue

1 reference

12 December 2020

Insulin-like growth factor-1 receptors and insulin-like growth factor-1-like activity in human primary breast cancer

1 reference

12 December 2020

Binding of epidermal growth factor and insulin-like growth-factor I in renal carcinoma and adjacent normal kidney tissue

1 reference

12 December 2020

Expression of insulin-like growth factor receptors in primary human thyroid neoplasms

1 reference

12 December 2020

Somatomedins: chemical and functional characteristics of the different molecular forms

1 reference

12 December 2020

Immunofluorescent localization of type II insulin-like growth factor receptor in rat liver and hepatoma cells

1 reference

12 December 2020

Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II.

1 reference

12 December 2020

A single receptor binds both insulin-like growth factor II and mannose-6-phosphate

1 reference

12 December 2020

Characterization of insulin-like growth factor I (IGF-I) receptors of human breast cancer cells

1 reference

12 December 2020

Expression of insulin-like growth factor-II transcripts in Wilms' tumour

1 reference

12 December 2020

Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level

1 reference

12 December 2020

Determinants of growth-promoting activity reside in the A-domain of insulin-like growth factor I.

1 reference

12 December 2020

Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis.

1 reference

12 December 2020

Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycemia

1 reference

12 December 2020

Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults

1 reference

12 December 2020

Evidence for autocrine mitogenic stimulation by somatomedin-C/insulin-like growth factor I on an established human lung cancer cell line

1 reference

12 December 2020

Temporal changes in the expression of the insulin-like growth factor II gene associated with tissue maturation in the human fetus.

1 reference

12 December 2020

Increased insulin-like growth factor II production and consequent suppression of growth hormone secretion: a dual mechanism for tumor-induced hypoglycemia.

1 reference

12 December 2020

Regulation of cathepsin-D and pS2 gene expression by growth factors in MCF7 human breast cancer cells

1 reference

12 December 2020

Evidence for autocrine production of IGF-1 in human thyroid adenomas

1 reference

12 December 2020

Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors

1 reference

12 December 2020

Somatostatin analogue SMS 201-995 reduces serum IGF-I levels in patients with neoplasms potentially dependent on IGF-I.

1 reference

12 December 2020

Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver

1 reference

12 December 2020

Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor

1 reference

12 December 2020

Serum insulin-like growth factor-I levels in patients with small cell lung cancer

1 reference

12 December 2020

Regulation of insulin and insulin-like growth factor (IGF) responsiveness by IGFs in rat hepatoma cells

1 reference

12 December 2020

Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene

1 reference

12 December 2020

Oncological applications of somatostatin analogues

1 reference

12 December 2020

Insulin-like growth factor (IGF)/somatomedin receptor subtypes: structure, function, and relationships to insulin receptors and IGF carrier proteins

1 reference

12 December 2020

Developmentally regulated expression of insulin-like growth factors by differentiated murine teratocarcinomas and extraembryonic mesoderm

1 reference

12 December 2020

Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells

1 reference

12 December 2020

Presence of somatomedin receptors on primary human breast and colon carcinomas

1 reference

12 December 2020

Soluble 34K binding protein inhibits the binding of insulin-like growth factor I to its cell receptors in human secretory phase endometrium: evidence for autocrine/paracrine regulation of growth factor action

1 reference

12 December 2020

Receptors for epidermal growth factor and insulin-like growth factor I and their relation to steroid receptors in human breast cancer

1 reference

12 December 2020

Structure of the receptor for insulin-like growth factor II: the puzzle amplified

1 reference

12 December 2020

Insulin-like growth factor 1 receptors in human breast cancer and their relation to estradiol and progesterone receptors

1 reference

12 December 2020

Evidence from monoclonal antibody studies that insulin stimulates deoxyribonucleic acid synthesis through the type I somatomedin receptor

1 reference

12 December 2020

Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues.

1 reference

12 December 2020

Enhanced expression of insulin-like growth factor II is not a necessary event in Wilms' tumour progression.

1 reference

12 December 2020

Multihormonal regulation of insulin-like growth factor-I-related protein in MCF-7 human breast cancer cells

1 reference

12 December 2020

Regulation of growth hormone and somatomedin-C secretion in postmenopausal women: effect of physiological estrogen replacement

1 reference

12 December 2020

Alveolar macrophages release an insulin-like growth factor I-type molecule

1 reference

12 December 2020

A human fibrosarcoma cell line producing multiplication stimulating activity (MSA)-related peptides

1 reference

12 December 2020

Production of immunoreactive insulin-like growth factor-I (IGF-I) and IGF-I binding proteins by human lung tumours

1 reference

12 December 2020

Insulin-like growth factor II-mediated proliferation of human neuroblastoma

1 reference

12 December 2020

Heterogeneity of the motility responses in malignant tumor cells: a biological basis for the diversity and homing of metastatic cells

1 reference

12 December 2020

Partial characterization of insulin-like growth factor I in primary human lung cancers using immunohistochemical and receptor autoradiographic techniques

1 reference

12 December 2020

Tumor hypoglycemia: relationship to high molecular weight insulin-like growth factor-II.

1 reference

12 December 2020

Suramin blockade of insulinlike growth factor I-stimulated proliferation of human osteosarcoma cells

1 reference

12 December 2020

Estrogen receptor-mediated direct and indirect antitumor effects of tamoxifen

1 reference

12 December 2020

Insulin-like growth factor gene expression in human smooth muscle tumors

1 reference

12 December 2020

Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding proteins and competitive binding studies

1 reference

12 December 2020

Steroid-sensitive proteins, growth hormone and somatomedin C in prostatic cancer: effects of parenteral and oral estrogen therapy

1 reference

12 December 2020

Characterization of the acid-labile subunit of the growth hormone-dependent insulin-like growth factor binding protein complex

1 reference

12 December 2020

Stimulation of collagen formation by insulin and insulin-like growth factor I in cultures of human lung fibroblasts

1 reference

12 December 2020

Transcripts of the insulin-like growth factors I and II in human hepatoma

1 reference

12 December 2020

Caloric restriction and 7,12-dimethylbenz(a)anthracene-induced mammary tumor growth in rats: alterations in circulating insulin, insulin-like growth factors I and II, and epidermal growth factor.

1 reference

12 December 2020

Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1.

1 reference

12 December 2020

Insulin-like growth factor I (IGF-I) production and the presence of IGF-I receptors in rat medullary thyroid carcinoma cell line 6-23 (clone 6)

1 reference

12 December 2020

Structural alteration of the insulin-like growth factor II-gene in Wilms tumour

1 reference

12 December 2020

Insulin and insulin-like growth factor I in brain tumors: binding and in vitro effects.

1 reference

12 December 2020

Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains

1 reference

12 December 2020

Characterization of insulin-like growth factor I and epidermal growth factor receptors in meningioma

1 reference

12 December 2020

Production of insulin-like growth factor binding proteins by small-cell lung cancer cell lines

1 reference

12 December 2020

Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice

1 reference

12 December 2020

The type I insulin-like growth factor receptor is a motility receptor in human melanoma cells

1 reference

12 December 2020

Insulin-like growth factor-I and its autocrine role in growth of MCF-7 human breast cancer cells in culture

1 reference

12 December 2020

A new gastric carcinoma cell line (LIM1839) derived from a young Caucasian male

1 reference

12 December 2020

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide

1 reference

12 December 2020

Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer

1 reference

12 December 2020

Tumour hypoglycaemia: raised tumour IGFII mRNA associated with reduced plasma somatomedins

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1992.65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 September 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1313689%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

1 reference