(Q67531174)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18408737%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

editorial

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title

ABT-737, proving to be a great tool even before it is proven in the clinic (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18408737%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1

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5 January 2020

author name string

D L Vaux

series ordinal

1

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publication date

1 May 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18408737%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

5 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18408737%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

15

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5 January 2020

issue

5

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5 January 2020

page(s)

807-808

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https://scigraph.springernature.com/pub.10.1038/cdd.2008.31

5 January 2020

exact match

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cites work

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.31

7 January 2021

Identifiers

DOI

10.1038/CDD.2008.31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18408737%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference