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Tumor suppressor genes
scientific article published on 01 September 1992
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scholarly article
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Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
review article
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Europe PubMed Central
title
Tumor suppressor genes
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
author name string
Lee NK
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
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15 September 2019
publication date
1 September 1992
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
published in
Head & Neck
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stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
page(s)
407-414
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
cites work
Suppression of Malignancy by Cell Fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation and cancer: statistical study of retinoblastoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the human retinoblastoma gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F transcription factor is a cellular target for the RB protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of alterations in the retinoblastoma gene and tumor grade in bone and soft-tissue sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered expression of the retinoblastoma gene product in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allele loss at the retinoblastoma locus in human ovarian cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Possible involvement of the retinoblastoma gene in undifferentiated sinonasal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53 proto-oncogene can act as a suppressor of transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 functions as a cell cycle control protein in osteosarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA binding domain is contained in the C-terminus of wild type p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of p53 as a sequence-specific DNA-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 can down-modulate the activity of various promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligomerization of oncoprotein p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conformation hypothesis for the suppressor and promoter functions ofp53in cell growth control and in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of human papillomavirus types 16 and 18 E6 proteins with p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of RB and p53 proteins in HPV-positive and HPV-negative cervical carcinoma cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BglII restriction fragment length polymorphisms at the human p53 gene locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biallelic Bgl II DNA polymorphism of the human p53 oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biallelic Apal polymorphism of the human p53 gene (TP53)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MspI polymorphism in intron 6 of p53 (TP53) detected by digestion of PCR products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of loss of heterozygosity in the p53 gene in renal cell carcinoma and bladder cancer using the polymerase chain reaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TP53 tumor suppressor gene: a model for investigating human mutagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational hot spot in the p53 gene in human hepatocellular carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent mutation of the p53 gene in human esophageal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a novel gene associated with low tumor metastatic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic alterations during colorectal-tumor development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifying tumor suppressor genes in human colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHED.2880140513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/HED.2880140513
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
PubMed publication ID
1399577
1 reference
stated in
Europe PubMed Central
PubMed publication ID
1399577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1399577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 September 2019
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