(Q67668050)

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Antinociceptive and substance P antagonistic effects of intrathecally injected spantide II in rat: no signs of motor impairment or neurotoxicity

scientific article published on 01 June 1990

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16 September 2019

Antinociceptive and substance P antagonistic effects of intrathecally injected spantide II in rat: no signs of motor impairment or neurotoxicity (English)

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16 September 2019

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based on heuristic

inferred from title

toxic encephalopathy

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based on heuristic

inferred from title

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10.1016/0167-0115(90)90104-5

https://api.crossref.org/works/10.1016/0167-0115(90)90104-5

1 November 2022

1 reference

10.1016/0167-0115(90)90104-5

https://api.crossref.org/works/10.1016/0167-0115(90)90104-5

1 November 2022

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10.1016/0167-0115(90)90104-5

https://api.crossref.org/works/10.1016/0167-0115(90)90104-5

1 November 2022

author name string

Z. Wiesenfeld-Hallin

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1 November 2022

X. J. Xu

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Europe PubMed Central

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1 November 2022

K. Kristensson

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1 November 2022

R. Håkanson

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1 November 2022

D. M. Feng

5

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Europe PubMed Central

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1 November 2022

K. Folkers

6

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Europe PubMed Central

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1 November 2022

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1697080

1 November 2022

publication date

1 June 1990

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16 September 2019

full work available at URL

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10.1016/0167-0115(90)90104-5

https://api.crossref.org/works/10.1016/0167-0115(90)90104-5

1 November 2022

https://api.elsevier.com/content/article/PII:0167011590901045?httpAccept=text/plain

1 reference

10.1016/0167-0115(90)90104-5

https://api.crossref.org/works/10.1016/0167-0115(90)90104-5

1 November 2022

Regulatory Peptides

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Europe PubMed Central

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16 September 2019

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16 September 2019

1

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16 September 2019

1-11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1697080%20AND%20SRC:MED&resulttype=core&format=json

16 September 2019

Regional distribution of substance P in the spinal cord and nerve roots of the cat and the effect of dorsal root section

2

1 reference

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Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons

3

1 reference

10.1016/0167-0115(90)90104-5

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Distribution of substance P-like immunoreactivity in the central nervous system of the rat—I. Cell bodies and nerve terminals

4

1 reference

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An immunohistochemical study of neuronal populations containing neuropeptides or gamma-aminobutyrate within the superficial layers of the rat dorsal horn

5

1 reference

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Release of substance P-like immunoreactivity from isolated spinal cord of newborn rat

6

1 reference

10.1016/0167-0115(90)90104-5

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Identification by high-performance liquid chromatography of immunoreactive substance P released from isolated rat spinal cord

7

1 reference

10.1016/0167-0115(90)90104-5

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Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo

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1 reference

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In vivo release of substance P in cat dorsal horn studied with microdialysis

9

1 reference

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Effects of substance P on functionally identified units in cat spinal cord

10

1 reference

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Effect of substance P in cat dorsal horn neurones activated by noxious stimuli

11

1 reference

10.1016/0167-0115(90)90104-5

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Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice

12

1 reference

10.1016/0167-0115(90)90104-5

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1 November 2022

Intrathecal substance P and somatostatin in rats: Behaviors indicative of sensation

13

1 reference

10.1016/0167-0115(90)90104-5

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Neurotransmitter candidates of somatosensory primary afferent fibres

15

1 reference

10.1016/0167-0115(90)90104-5

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Chemical design of antagonists of substance P

16

1 reference

10.1016/0167-0115(90)90104-5

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A synthetic peptide as an antagonist of substance P

17

1 reference

10.1016/0167-0115(90)90104-5

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Inhibition of antidromic and substance P-induced vasodilatation by a substance P antagonist

18

1 reference

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A specific substance P antagonist blocks smooth muscle contractions induced by non-cholinergic, non-adrenergic nerve stimulation

19

1 reference

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Design and Synthesis of Effective Antagonists of Substance P

20

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Synthesis and biological activities of substance P antagonists.

21

1 reference

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Substance P antagonists active in vitro and in vivo.

22

1 reference

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The mechanism of action of a substance P antagonist (D-Pro2, D-Trp7,9)-SP.

23

1 reference

10.1016/0167-0115(90)90104-5

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Biological evaluation of substance P antagonists

24

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10.1016/0167-0115(90)90104-5

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Sensory and Motor Functions of Spinal Cord Substance P

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Substance p anatogue blocks sp-induced facilitation of a spinal nociceptive reflex

26

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Behavioural and antinociceptive effects of intrathecally injected substance P analogues in mice.

27

1 reference

10.1016/0167-0115(90)90104-5

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Effects of substance P analogues on spinal dorsal horn neurons

28

1 reference

10.1016/0167-0115(90)90104-5

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Lntrathecal (D-Pro2, D-Trp7,9)-SP elicits hypoalgesia and motor blockade in the rat and antagonizes noxious responses induced by substance P

29

1 reference

10.1016/0167-0115(90)90104-5

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Analgesic effect of antagonists of substance P

30

1 reference

10.1016/0167-0115(90)90104-5

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Antinociceptive and neurotoxic actions of substance P analogues in the rat's spinal cord after intrathecal administration

31

1 reference

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The behavioural effects of intrathecally administered [d-PRO2,d-TRP7,9]-substance P, an analogue with presumed antagonist actions, in the rat

33

1 reference

10.1016/0167-0115(90)90104-5

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Intrathecal substance P analogue causes motor dysfunction in the rat

34

1 reference

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Evaluation of (D-Pro2, D-Trp7,9)-substance P as an antagonist of substance P responses in the rat central nervous system.

35

1 reference

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D-Arg1, D-Trp7,9, Leu11-substance P (spantide) does not antagonize substance P-induced hyperexcitability of the nociceptive flexion withdrawal reflex in the rat

36

1 reference

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Immunohistochemical evidence for a “neurotoxic” action of (D-Pro2, D-Trp7,9)-substance P, an analogue with substance P antagonistic activity

37

1 reference

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Substance P antagonists and the role of tachykinins in non-cholinergic bronchoconstriction

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Tachykinin antagonists have potent local anaesthetic actions

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Substance P antagonists and analgesia: a review of the hypothesis

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Increased potency of antagonists of substance P having asparagine in position 6.

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Substance P and somatostatin modulate spinal cord excitability via physiologically different sensory pathways.

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Chronic catheterization of the spinal subarachnoid space.

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Species differences in the behavioral toxicity produced by intrathecal substance P antagonists: relationship to analgesia

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Antinociceptive effects in mice after intrathecal injection of a substance P receptor antagonist, Spantide: lack of 'neurotoxic' action

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Characterization of spinal actions of four substance P analogues

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Immunohistochemical evidence for separate populations of somatostatin-containing and substance P-containing primary afferent neurons in the rat

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Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat

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Intrathecal somatostatin modulates spinal sensory and reflex mechanisms: behavioral and electrophysiological studies in the rat

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Behavioural assessment as substance P antagonists in mice

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Analgesic activities of spinal cord substance P antagonists implicate substance P as a neurotransmitter of pain sensation

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Identifiers

10.1016/0167-0115(90)90104-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1697080%20AND%20SRC:MED&resulttype=core&format=json

16 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1697080%20AND%20SRC:MED&resulttype=core&format=json

16 September 2019

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