(Q67708830)

English

Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations

scientific article published on 01 July 1991

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

1 reference

10.1007/BF00167387

https://api.crossref.org/works/10.1007/BF00167387

8 November 2022

author name string

H. von der Leyen

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

U. Mende

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

W. Meyer

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

J. Neumann

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

M. Nose

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

W. Schmitz

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

H. Scholz

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

J. Starbatty

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

B. Stein

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

H. Wenzlaff

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1723153

8 November 2022

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1723153

8 November 2022

publication date

1 July 1991

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

full work available at URL

http://link.springer.com/article/10.1007/BF00167387/fulltext.html

1 reference

10.1007/BF00167387

https://api.crossref.org/works/10.1007/BF00167387

8 November 2022

http://link.springer.com/content/pdf/10.1007/BF00167387.pdf

Portable Document Format

1 reference

10.1007/BF00167387

https://api.crossref.org/works/10.1007/BF00167387

8 November 2022

http://link.springer.com/content/pdf/10.1007/BF00167387

1 reference

10.1007/BF00167387

https://api.crossref.org/works/10.1007/BF00167387

8 November 2022

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

344

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

90-100

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1723153%20AND%20SRC:MED&resulttype=core&format=json

17 September 2019

https://scigraph.springernature.com/pub.10.1007/bf00167387

0 references

Additive effects of dobutamine and amrinone on myocardial contractility and ventricular performance in patients with severe heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cyclic AMP in the positive inotropic effect mediated by beta 1- and beta 2-adrenoceptors in isolated human right atrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine inhibition of catecholamine-induced increase in force of contraction in guinea-pig atrial and ventricular heart preparations. Evidence against a cyclic AMP- and cyclic GMP-dependent effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive inotropic and vasodilatory actions of saterinone in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of beta-adrenoceptor density and evaluation of positive inotropic responses in isolated, diseased human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inotropic drugs and their mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets. Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in myocardial Gi-proteins in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UD-CG 115 ? a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vasodilator and inotropic drugs for the treatment of chronic heart failure: distinguishing hype from hope

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inotropic and vasodilator effects of amrinone on isolated human tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the effectiveness of milrinone to increase force of contraction by stimulation of cardiac beta-adrenoceptors in the failing human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Chronic Heart Failure on the Capacity of Glucagon to Enhance Contractility and Adenyl Cyclase Activity of Human Papillary Muscles

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of the normal and failing isolated human heart: Decreased response of failing heart to isoproterenol

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of the sympathetic nervous system and renin-angiotensin system assessed by plasma hormone levels and their relation to hemodynamic abnormalities in congestive heart failure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effectiveness of inotropic agents in isolated cardiac preparations from the human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on the intracoronary administration of milrinone and dobutamine to patients with congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of cyclic AMP phosphodiesterase from various human tissues by milrinone, a potent cardiac bipyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and inotropic potential of forskolin in the human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular effects of the positive inotropic agents pimobendan and sulmazole in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved assay of cyclic 3',5'-nucleotide phosphodiesterases with QAE-Sephadex columns

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and long-term hemodynamic effects of pimobendan (UD-CG 115 BS) in comparison with captopril.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurohormonal interactions and adaptations in congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heart failure in outpatients: a randomized trial of digoxin versus placebo

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basal and isoprenaline-stimulated cAMP content in failing versus nonfailing human cardiac preparations

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pimobendane (UD-CG 115 BS) in chronic congestive heart failure. Short-term and one-month effects of a new inotropic vasodilating agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple cyclic nucleotide phosphodiesterase activities from rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of cAMP phosphodiesterase III activity by the cardiotonic agent saterinone in guinea pig myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma norepinephrine in congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemodynamic profile of BM 14.478: a new positive inotropic and vasodilating agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/1723153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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