(Q68033249)

English

Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice

scientific article published on 01 January 1991

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

pharmacokinetics

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

author name string

P Kestell

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

W A Denny

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

B C Baguley

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

publication date

1 January 1991

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

Cancer Chemotherapy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

28

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

409-413

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

https://scigraph.springernature.com/pub.10.1007/bf00685815

0 references

Flavone acetic acid and plasma protein binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictive Model for Plasma Concentration-Versus-Time Profiles of Investigational Anticancer Drugs in Patientsi

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential antitumor agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid (NSC 347512) induces haemorrhagic necrosis of mouse colon 26 and 38 tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid pharmacokinetics in nude mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent pharmacokinetics of flavone acetic acid in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Light-induced breakdown of flavone acetic acid and xanthenone analogues in solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-Dependent Pharmacokinetics: Emphasis on Phase I Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid alkalinisation for flavone acetic acid administration: a potentially hazardous procedure

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics and causes of dose-dependent pharmacokinetics of flavone-8-acetic acid (LM-975; NSC-347512) in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and clinical pharmacology study of intravenous flavone acetic acid (NSC 347512).

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid (LM 975, NSC 347512). A novel antitumor agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and pharmacokinetic study of flavone acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trials of flavone acetic acid in advanced malignant melanoma and colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of xanthenone-4-acetic acid in mouse plasma by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between in vivo induction of cytokine gene expression by flavone acetic acid and strict dose dependency and therapeutic efficacy against murine renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic alkalinization inhibits the ability of flavone acetic acid to augment natural killer activity, induce cytokine gene expression, and synergize with interleukin 2 for the treatment of murine renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of natural killer cell activity by the antitumour compound flavone acetic acid (NSC 347 512).

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid: a nonlinear pharmacokinetic model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1934244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00685815

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1934244%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

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