(Q68332109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

title

Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

49 Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6 (English)

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

29 October 2022

author name string

T. Kronbach

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686064

29 October 2022

language of work or name

English

0 references

publication date

1 January 1991

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

published in

Methods in Enzymology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

volume

206

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

page(s)

509-517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

23 September 2019

cites work

1

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

29 October 2022

2

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms

29 October 2022

3

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

29 October 2022

4

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism)--increased Michaelis is Constant (Km) and loss of stereoselectivity of bufuralol 1'-hydroxylation in poor metabolizers

29 October 2022

5

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Stereo- and regioselectivity of hepatic oxidation in man--effect of the debrisoquine/sparteine phenotype on bufuralol hydroxylation

29 October 2022

8

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Biochemical and Biophysical Research Communications

29 October 2022

9

34

399

Dayer

1990

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation

29 October 2022

10

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

High-performance liquid chromatographic comparison of in vivo and in vitro drug metabolism

29 October 2022

11

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone

29 October 2022

12

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Evidence for two closely related isozymes of arylamine N-acetyltransferase in human liver

29 October 2022

13

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiency

29 October 2022

14

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography

29 October 2022

15

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Bufuralol metabolism in human liver: a sensitive probe for the debrisoquine-type polymorphism of drug oxidation

29 October 2022

18

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

29 October 2022

19

1 reference

https://api.crossref.org/works/10.1016/0076-6879(91)06120-R

29 October 2022

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1686064%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

1 reference