(Q68774841)

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Relationship between the inhibitory potencies of thiorphan and retrothiorphan enantiomers on thermolysin and neutral endopeptidase 24.11 and their interactions with the thermolysin active site by computer modelling

scientific article published on 01 September 1987

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27 September 2019

Relationship between the inhibitory potencies of thiorphan and retrothiorphan enantiomers on thermolysin and neutral endopeptidase 24.11 and their interactions with the thermolysin active site by computer modelling (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3478046%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

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T Benchetrit

1

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27 September 2019

M C Fournié-Zaluski

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3478046%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

B P Roques

3

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27 September 2019

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1 September 1987

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27 September 2019

Biochemical and Biophysical Research Communications

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3478046%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

147

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27 September 2019

3

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27 September 2019

1034-1040

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27 September 2019

The purification and specificity of a neutral endopeptidase from rabbit kidney brush border

1 reference

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1 reference

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The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

1 reference

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Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

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Refined crystal structure of carboxypeptidase A at 1.54 A resolution

1 reference

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7 January 2021

Three-dimensional structure of thermolysin

1 reference

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7 January 2021

1H NMR configurational correlation for retro-inverso dipeptides: application to the determination of the absolute configuration of "enkephalinase" inhibitors. Relationships between stereochemistry and enzyme recognition

1 reference

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7 January 2021

Structure of a mercaptan-thermolysin complex illustrates mode of inhibition of zinc proteases by substrate-analogue mercaptans

1 reference

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7 January 2021

The adsorption of enkephalin to porous polystyrene beads: a simple assay for enkephalin hydrolysis.

1 reference

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7 January 2021

Inhibition of enkephalin-degrading enzymes from rat brain and of thermolysin by amino acid hydroxamates

1 reference

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7 January 2021

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

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7 January 2021

Representation of a protein molecule as a tree and application to modular computer programs which calculate and modify atomic coordinates

1 reference

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7 January 2021

Differences in the structural requirements for selective interaction with neutral metalloendopeptidase (enkephalinase) or angiotensin-converting enzyme. Molecular investigation by use of new thiol inhibitors

1 reference

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7 January 2021

Enantiomers of [R,S]-thiorphan: dissociation of analgesia from enkephalinase A inhibition

1 reference

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7 January 2021

Computer-aided drug design

1 reference

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A unique geometry of the active site of angiotensin-converting enzyme consistent with structure-activity studies

1 reference

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7 January 2021

Identifiers

10.1016/S0006-291X(87)80174-2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3478046%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3478046%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

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