(Q69376820)

English

Dependence of hydrogen peroxide formation in rat liver microsomes on the molecular structure of cytochrome P-450 substrates: a study with barbiturates and beta-adrenoceptor antagonists

scientific article published on 01 April 1989

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

Dependence of hydrogen peroxide formation in rat liver microsomes on the molecular structure of cytochrome P-450 substrates: a study with barbiturates and beta-adrenoceptor antagonists (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

author name string

A Bast

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

P A Goossens

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

E M Savenije-Chapel

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

publication date

1 April 1989

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

European Journal of Drug Metabolism and Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

14

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

93-100

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2574109%20AND%20SRC:MED&resulttype=core&format=json

1 October 2019

https://scigraph.springernature.com/pub.10.1007/bf03190847

0 references

Mechanisms of lipid peroxidation dependent upon cytochrome P-450 LM2

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stoichiometric cooperation of NADPH and hexobarbital in hepatic microsomes during the catalysis of hydrogen peroxide formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidase and oxygenase function of the microsomal cytochrome P450 monooxygenase system

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hexobarbital-binding, hydroxylation and hexobarbital-dependent hydrogen peroxide production in hepatic microsomes of guinea pig, rat and rabbit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Product inhibition in orphenadrine metabolism as a result of a stable cytochrome P-450-metabolic intermediate complex formed during the disposition of mono-N-desmethylorphenadrine (tofenacine) in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide in hepatic microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mono-oxygenase and oxidase activity of rat-hepatic cytochrome P-450 by H2-receptor blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 oxidase activity and its role in NADPH dependent lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the mechanisms of glutathione depletion in hepatocytes exposed to morphine and ethylmorphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic differences in oxygen toxicity are correlated with cytochrome P-450 inducibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calculation of competitive inhibition of substrate binding to cytochrome P-450 illustrated by the interaction of d,l-propranolol with d,l-hexobarbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectral evidence for weak ligand in sixth position of hepatic microsomal cytochrome P-450 low spin ferric iron in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of synthetic antioxidants on hydrogen peroxide formation, oxyferro cytochrome P-450 concentration and oxygen consumption in liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ks values of some homologous series of barbiturates and the relationship with the lipophilicity and metabolic clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectral interaction of orphenadrine and its metabolites with oxidized and reduced hepatic microsomal cytochrome P-450 in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2574109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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