(Q69522468)

English

Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis

scientific article published on 01 August 1989

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2668162%20AND%20SRC:MED&resulttype=core&format=json

2 October 2019

Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2668162%20AND%20SRC:MED&resulttype=core&format=json

2 October 2019

author name string

R J Smith

1

1 reference

Europe PubMed Central

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2 October 2019

N A Rohloff

2

1 reference

Europe PubMed Central

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2 October 2019

L M Sam

3

1 reference

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2 October 2019

J M Justen

4

1 reference

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2 October 2019

M R Deibel

5

1 reference

Europe PubMed Central

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2 October 2019

J C Cornette

6

1 reference

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2 October 2019

publication date

1 August 1989

1 reference

Europe PubMed Central

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2 October 2019

1 reference

Europe PubMed Central

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2 October 2019

13

1 reference

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2 October 2019

367-382

1 reference

Europe PubMed Central

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2 October 2019

4

1 reference

Europe PubMed Central

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2 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00914921

0 references

A common class of receptors for the two types of porcine interleukin-1 on articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An interleukin 1 like factor stimulates bone resorption in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro activation of human chondrocytes and synoviocytes by a human interleukin-1-like factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteoglycan- and collagen-degrading enzymes from human interleukin 1-stimulated chondrocytes from several species: proteoglycanase and collagenase inhibitors as potentially new disease-modifying antiarthritic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of IL-1 genes in human and bovine chondrocytes: a mechanism for autocrine control of cartilage matrix degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a high-affinity receptor for native human interleukin 1 beta and interleukin 1 alpha on normal human lung fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antiinflammatory drugs on human interleukin-1-induced cartilage degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An update on human interleukin-1: from molecular biology to clinical relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autocrine stimulation of interleukin 1 beta in acute myelogenous leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 2-independent stimulation of rabbit chondrocyte collagenase and prostaglandin E2 production by an interleukin 1-like factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of human recombinant tumor necrosis factor-alpha and interleukin 1 on the synthesis of glycosaminoglycan and DNA in cultured rat costal chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of connective tissue metabolism by partially purified human interleukin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage Factor that Induces Neutral Protease Secretion by Normal Rabbit Chondrocytes. Studies of Some Properties and Effects on Metabolism of Chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of bacterial lipopolysaccharides on the biosynthesis and release of proteoglycans from calf articular cartilage cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine modulation of chondrocyte proteinase release

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of antiinflammatory drugs on the release from porcine synovial tissue in vitro of interleukin 1 like cartilage degrading activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pig interleukin 1 (catabolin) is a potent stimulator of bone resorption in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of synovial catabolin on cartilage synthetic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cartilage remodeling by IL-1: evidence for autocrine synthesis of IL-1 by chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1-like activities in synovial fluids of patients with rheumatoid arthritis and traumatic synovitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of chondrocyte responses to a human interleukin 1-like factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human interleukin 1 mediates cartilage matrix degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Articular cartilage cultured with catabolin (pig interleukin 1) synthesizes a decreased number of normal proteoglycan molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of collagenase and neutral proteases by articular chondrocytes: Stimulation by a macrophage-derived factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial lipopolysaccharides induce in vitro degradation of cartilage matrix through chondrocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of synovial tissue on the breakdown of articular cartilage in organ culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of catabolin, a protein fro synovium which induces degradation of cartilage in organ culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin-1 in human B-cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a specific antiserum to rabbit stromelysin and demonstration of the synthesis of collagenase and stromelysin by stimulated rabbit articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell surface receptors for interleukin-1 alpha and interleukin-1 beta are identical

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a common class of high affinity receptors for both types of porcine interleukin-1 on connective tissue cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of an interleukin-1-like factor from human joint effusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mononuclear cell-conditioned medium containing mononuclear cell factor (MCF), homologous with interleukin 1, stimulates collagen and fibronectin synthesis by adherent rheumatoid synovial cells: effects of prostaglandin E2 and indomethacin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystallization of purified recombinant human interleukin-1 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cartilage catabolic factor from synovium

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chondrocyte activation in response to factor(s) produced by a continuous line of lapine synovial fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2668162

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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