(Q69749394)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

title

Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

author name string

K Brøsen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

L F Gram

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

publication date

1 January 1989

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Clinical Pharmacology

5 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

page(s)

155-160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2792169%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/bf00558224

5 October 2019

exact match

0 references

cites work

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

1 reference

12 December 2020

A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

1 reference

12 December 2020

Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism

1 reference

12 December 2020

The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine

1 reference

12 December 2020

In vitro evidence against the oxidation of quinidine by the sparteine/debrisoquine monooxygenase of human liver

1 reference

12 December 2020

Sparteine oxidation polymorphism: a family study

1 reference

12 December 2020

Phenotypic consistency in hydroxylation of desmethylimipramine and debrisoquine in healthy subjects and in human liver microsomes

1 reference

12 December 2020

Sparteine oxidation polymorphism in Denmark.

1 reference

12 December 2020

First-pass metabolism of imipramine in man

1 reference

12 December 2020

Sparteine oxidation is practically abolished in quinidine-treated patients

1 reference

12 December 2020

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1 reference

12 December 2020

Steady-state kinetics of imipramine in patients

1 reference

12 December 2020

Imipramine demethylation and hydroxylation: impact of the sparteine oxidation phenotype

1 reference

12 December 2020

Pharmacokinetics and metabolism of quinidine in extensive and poor metabolisers of sparteine

1 reference

12 December 2020

Imipramine metabolites in blood of patients during therapy and after overdose

1 reference

12 December 2020

Inhibition of desipramine 2-hydroxylation by quinidine and quinine

1 reference

12 December 2020

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

1 reference

12 December 2020

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1 reference

12 December 2020

Hydroxylation of desmethylimipramine: dependence on the debrisoquin hydroxylation phenotype

1 reference

12 December 2020

Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes.

1 reference

12 December 2020

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

12 December 2020

Amitriptyline metabolism: association with debrisoquin hydroxylation in nonsmokers

1 reference

12 December 2020

First-pass metabolism of imipramine and desipramine: Impact of the sparteine oxidation phenotype

1 reference

12 December 2020

Oxidation of tricyclic antidepressant drugs, debrisoquine and 7-ethoxyresorufin, by human liver preparations

1 reference

12 December 2020

Purification of a desmethylimipramine and debrisoquine hydroxylating cytochrome P-450 from human liver

1 reference

12 December 2020

Interindividual differences in amitriptyline demethylation

1 reference

12 December 2020

Effects of perphenazine on imipramine metabolism in man

1 reference

12 December 2020

Metabolism of tricyclic antidepressants. A review

1 reference

12 December 2020

Steady-state levels of imipramine and its metabolites: significance of dose-dependent kinetics

1 reference

12 December 2020

Inhibition of sparteine oxidation in human liver by tricyclic antidepressants and other drugs

1 reference

12 December 2020

Extensive metabolizers of debrisoquine become poor metabolizers during quinidine treatment

1 reference

12 December 2020