(Q69848134)

English

Function and stimulus-specific effects of phorbol 12-myristate 13-acetate on human polymorphonuclear neutrophils: autoregulatory role for protein kinase C in signal transduction

scientific article published on 01 December 1988

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

Function and stimulus-specific effects of phorbol 12-myristate 13-acetate on human polymorphonuclear neutrophils: autoregulatory role for protein kinase C in signal transduction (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

polymorphonuclear neutrophil

0 references

author name string

R J Smith

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

J M Justen

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

L M Sam

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

publication date

1 December 1988

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

597-611

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2851553%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00914321

0 references

The effect of a protein kinase C inhibitor, H-7, on human neutrophil oxidative burst and degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular control of human neutrophil secretion. I. C5a-induced stimulus-specific desensitization and the effects of cytochalasin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inositol trisphosphate and diacylglycerol: two interacting second messengers

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of formylmethionyl-leucyl-phenylalanine stimulation of inositol trisphosphate accumulation in rabbit neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol myristate acetate and the calcium ionophore A23187 synergistically induce release of LTB4 by human neutrophils: involvement of protein kinase C activation in regulation of the 5-lipoxygenase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of neutrophil responsiveness caused by phorbol esters is blocked by the protein kinase C inhibitor H7

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein kinase C inhibitors H-7 and H-9 fail to inhibit human neutrophil activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of effect of N-formyl-methionyl-leucyl-phenylalanine on leukotriene synthesis in human polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of an inhibitor of protein kinase C on human polymorphonuclear leukocyte degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of nadph oxidase of human neutrophils. Potentiation of chemotactic peptide by a diacylglycerol

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of guanine nucleotide regulatory protein in polyphosphoinositide degradation and activation of phagocytic leukocytes by chemoattractants

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulus amplification by PAF and LTB4 in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotaxin receptors of neutrophils: evidence that F-methionyl peptides and pepstatin share a common receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoattractant-mediated stimulation of the respiratory burst in human polymorphonuclear leukocytes may require appearance of protein kinase activity in the cells' particulate fraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidylinositol 4,5-bisphosphate hydrolysis in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of human neutrophil superoxide anion generation by the calcium antagonist 8-(N,N-diethylamino)-octyl-(3,4,5-trimethoxy) benzoate hydrochloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pepstatin A—A human leukocyte chemoattractant

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol myristate acetate receptors in human polymorphonuclear neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C-mediated negative-feedback inhibition of unstimulated and bombesin-stimulated polyphosphoinositide hydrolysis in Swiss-mouse 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical, metabolic and morphological characteristics of human neutrophil activation with pepstatin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pepstatin, a new pepsin inhibitor produced by Actinomycetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory action of phorbol myristate acetate on histamine secretion and polyphosphoinositide turnover induced by compound 48/80 in mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of NADPH oxidase in human neutrophils. Synergism between fMLP and the neutrophil products PAF and LTB4

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol 12, myristate 13, acetate potentiates the respiratory burst while inhibits phosphoinositide hydrolysis and calcium mobilization by formyl-methionyl-leucyl-phenylalanine in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of chemotactic peptide-induced phosphoinositide hydrolysis by phorbol esters through the activation of protein kinase C in differentiated human leukemia (HL-60) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism between A23187 and 1-oleoyl-2-acetyl-glycerol in superoxide production by human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonate metabolites, platelet-activating factor, and the mobilization of protein kinase C in human polymorphonuclear neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new generation of Ca2+ indicators with greatly improved fluorescence properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model for leukocyte regulation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive inhibition by diacylglycerol of specific phorbol ester binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of protein kinase C in cell surface signal transduction and tumour promotion

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pepstatin A-induced degranulation and superoxide anion generation by human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulus response coupling in the human neutrophil. II. Temporal analysis of changes in cytosolic calcium and calcium efflux

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-(5-isoquinol inesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase c in rabbit platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol 12-myristate, 13-acetate potentiates the action of the calcium ionophore in stimulating arachidonic acid release and production of phosphatidic acid in rabbit neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human neutrophil chemotaxis by the protein kinase inhibitor, 1-(5-isoquinolinesulfonyl) piperazine

1 reference

https://pubmed.ncbi.nlm.nih.gov/2851553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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