(Q69851986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2854217%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

title

Cyclic AMP-dependent and cyclic AMP-independent actions of a novel cardiotonic agent, OPC-8212 (English)

1 reference

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6 October 2019

2

1 reference

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6 October 2019

author name string

S T Rapundalo

1

1 reference

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6 October 2019

S A Harrison

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2854217%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

J A Beavo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2854217%20AND%20SRC:MED&resulttype=core&format=json

6 October 2019

A Schwartz

5

1 reference

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6 October 2019

publication date

1 December 1988

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Naunyn-Schmiedeberg's Archives of Pharmacology

6 October 2019

published in

1 reference

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6 October 2019

volume

338

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6 October 2019

issue

6

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6 October 2019

page(s)

692-698

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Removal of inactivation and blockade of cardiac Na+ channels by DPI 201-106: different voltage-dependencies of the drug actions

6 October 2019

cites work

1 reference

12 December 2020

The effect of the duration of the action potential on contraction in the mammalian heart muscle

1 reference

12 December 2020

Transmembrane Na+ and Ca2+ electrochemical gradients in cardiac muscle and their relationship to force development

1 reference

12 December 2020

UD-CG 115 ? a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle

1 reference

12 December 2020

Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart

1 reference

12 December 2020

Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle

1 reference

12 December 2020

In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals

1 reference

12 December 2020

Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues

1 reference

12 December 2020

Identification and properties of cyclic nucleotide phosphodiesterases

1 reference

12 December 2020

Purification of two calcium/calmodulin-dependent forms of cyclic nucleotide phosphodiesterase by using conformation-specific monoclonal antibody chromatography

1 reference

12 December 2020

Cardioactive substances that prolong the open state of sodium channels

1 reference

12 December 2020

Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility

1 reference

12 December 2020

Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs

1 reference

12 December 2020

Evidence for possible increase of sodium channel open time and involvement of Na/Ca exchange by a new positive inotropic drug: OPC-8212.

1 reference

12 December 2020

The role of intracellular sodium activity in the anti-arrhythmic action of local anaesthetics in sheep Purkinje fibres

1 reference

12 December 2020

In vitro investigations on a new positive inotropic and vasodilating agent (BM 14.478) that increases myocardial cyclic AMP content and myofibrillar calcium sensitivity

1 reference

12 December 2020

Negative inotropic effects of tetrodotoxin and seven class 1 antiarrhythmic drugs in relation to sodium channel blockade

1 reference

12 December 2020

Hemodynamic and electrophysiological effects of a novel positive inotropic drug, OPC-8212, in normal and "failing" guinea pig heart preparations

1 reference

12 December 2020

Cardiovascular properties of a new cardiotonic agent: MDL 17,043 (1.3-dihydro-4-methyl-5-[4-(methylthio)-benzoyl]-2H-imidazol-2-one).

1 reference

12 December 2020

Pharmacological actions of various inotropic agents

1 reference

12 December 2020

Effects of a new positive inotropic agent, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212) and its solvent sulfolane on isolated heart preparations of the rat, guinea pig, and dog.

1 reference

12 December 2020

DPI 201-106, a novel cardioactive agent. Combination of cAMP-independent positive inotropic, negative chronotropic, action potential prolonging and coronary dilatory properties.

1 reference

12 December 2020

Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme

1 reference

12 December 2020

LY195115: a potent, selective inhibitor of cyclic nucleotide phosphodiesterase located in the sarcoplasmic reticulum.

1 reference

12 December 2020

Effects of new inotropic agents on Ca++ sensitivity of contractile proteins

1 reference

12 December 2020

Differential inhibition of cardiac cyclic nucleotide phosphodiesterase isozymes by cardiotonic drugs

1 reference

12 December 2020

Increase in Ca++ sensitivity of the contractile system by MCI-154, a novel cardiotonic agent, in chemically skinned fibers from the guinea pig papillary muscles

1 reference

12 December 2020

The effect of a new positive inotropic agent, 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), on thin bundles of skinned fibers from cardiac muscle.

1 reference

12 December 2020

Studies on the mechanism of action of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), a new positive inotropic drug. Enzyme activities and Ca2+ transport processes of sarcolemma and intracellular organelles

1 reference

12 December 2020

Ionic mechanism of inotropic effect of veratrine on frog heart

1 reference

12 December 2020

Adrenaline-like effects of intracellular iontophoresis of cyclic AMP in cardiac Purkinje fibres

1 reference

12 December 2020

Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts.

1 reference

12 December 2020

Electro-mechanical effects of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), a new positive inotropic agent. Isolated adult canine Purkinje strands and ventricular trabeculae

1 reference

12 December 2020

Effect of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212) on the membrane currents of rabbit sino-atrial node cells

1 reference

12 December 2020

Membrane current changes responsible for the positive inotropic effect of OPC-8212, a new positive inotropic agent, in single ventricular cells of the guinea pig heart

1 reference

12 December 2020

Myocardial actions of milrinone: characterization of its mechanism of action

1 reference

12 December 2020

The role of sodium channels in the effects of the cardiotonic compound DPI 201-106 on contractility and membrane potentials in isolated mammalian heart preparations.

1 reference

12 December 2020