(Q70109856)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

title

Modeling of substrate elimination by the liver: has the albumin receptor model superseded the well-stirred model? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

author name string

D J Morgan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

D B Jones

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

R A Smallwood

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

language of work or name

English

0 references

publication date

1 November 1985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

volume

5

1 reference

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8 October 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

page(s)

1231-1235

1 reference

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Internal perfusion studies demonstrating GABA-induced chloride responses in frog primary afferent neurons

8 October 2019

cites work

1 reference

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7 January 2021

Altered Hepatic Blood Flow and Drug Disposition1

1 reference

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7 January 2021

On the uptake of materials by the intact liver. The transport and net removal of galactose

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7 January 2021

Factors affecting drug metabolism

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7 January 2021

Clearance concepts in pharmacokinetics

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7 January 2021

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Commentary: a physiological approach to hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Use of unbound drug concentration in blood to discriminate between two models of hepatic drug elimination

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Hepatic elimination of flowing substrates: the distributed model

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

A family of models for the elimination of substrate in the liver

1 reference

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7 January 2021

Theoretic aspects of pharmacokinetic drug interactions

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Linear range of Na+ pump in sciatic nerve of frog

1 reference

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7 January 2021

Influence of plasma protein binding kinetics on hepatic clearance assessed from a “tube” model and a “well-stirred” model

1 reference

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7 January 2021

Hepatic elimination of drugs with concentration-dependent serum protein binding

1 reference

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7 January 2021

Protein binding and hepatic clearance: discrimination between models of hepatic clearance with diazepam, a drug of high intrinsic clearance, in the isolated perfused rat liver preparation.

1 reference

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7 January 2021

Variation in hepatic extraction ratio with unbound drug fraction: discrimination between models of hepatic drug elimination.

1 reference

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7 January 2021

Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liverin situ preparation

1 reference

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7 January 2021

Models of hepatic drug clearance: discrimination between the ‘well stirred’ and ‘parallel-tube’ models

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Michaelis-Menten kinetics of galactose elimination by the isolated perfused pig liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

How small is the functional variability of liver sinusoids?

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Current models of hepatic pharmacokinetics: flow effects on kinetic constants of ethanol elimination in perfused rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Perfusion-limited of plasma drug binding on hepatic drug extraction

1 reference

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7 January 2021

Determinants of drug disposition in patients with cirrhosis.

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7 January 2021

Influence of Food Intake on Presystemic Clearance of Drugs

1 reference

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7 January 2021

Hepatic Clearance Measurements and Pharmacokinetics

1 reference

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7 January 2021

Albumin binding and hepatic uptake: the importance of model selection

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Receptor for Albumin on the Liver Cell Surface May Mediate Uptake of Fatty Acids and Other Albumin-Bound Substances

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Albumin helps mediate removal of taurocholate by rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Albumin does not mediate the removal of taurocholate by the rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

A linear method for determining liver sinusoidal and extravascular volumes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Hepatic sequestration and biliary secretion of epidermal growth factor: evidence for a high-capacity uptake system

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Acinar heterogeneity in hepatic transport of dibromosulfophthalein and ouabain studied by autoradiography, normal and retrograde perfusions and computer simulation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Zonal changes in the rat liver after chronic administration of phenobarbitone: An ultrastructural, morphometric and biochemical correlation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Hepatic bilirubin uptake in the isolated perfused rat liver is not facilitated by albumin binding

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Plasma clearance of sulfobromophthalein and its interaction with hepatic binding proteins in normal and analbuminemic rats: is plasma albumin essential for vectorial transport of organic anions in the liver?

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

A carrier-protein receptor is not a prerequisite for avid hepatic elimination of highly bound compounds: a study of propranolol elimination by the isolated perfused rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Effect of albumin binding on extraction of sulfobromophthalein by perfused elasmobranch liver: evidence for dissociation-limited uptake.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.1840050629

7 January 2021

Identifiers

DOI

10.1002/HEP.1840050629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2998965%20AND%20SRC:MED&resulttype=core&format=json

8 October 2019

1 reference