(Q70797485)

English

Methotrexate resistance in al L1210 cell line resulting from increased dihydrofolate reductase, decreased thymidylate synthetase activity, and normal membrane transport. Computer simulations based on network thermodynamics

scientific article published on June 10, 1981

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Europe PubMed Central

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14 October 2019

Methotrexate resistance in al L1210 cell line resulting from increased dihydrofolate reductase, decreased thymidylate synthetase activity, and normal membrane transport. Computer simulations based on network thermodynamics (English)

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14 October 2019

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computer simulation

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10.1016/S0021-9258(19)69266-5

https://api.crossref.org/works/10.1016/S0021-9258(19)69266-5

27 March 2024

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10.1016/S0021-9258(19)69266-5

https://api.crossref.org/works/10.1016/S0021-9258(19)69266-5

27 March 2024

author name string

J. C. White

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27 March 2024

I. D. Goldman

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1 June 1981

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14 October 2019

10 June 1981

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7240168

27 March 2024

full work available at URL

https://doi.org/10.1016/s0021-9258(19)69266-5

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Europe PubMed Central

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27 March 2024

http://intl.jbc.org/cgi/content/abstract/256/11/5722

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Europe PubMed Central

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27 March 2024

https://api.elsevier.com/content/article/PII:S0021925819692665?httpAccept=text/xml

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10.1016/S0021-9258(19)69266-5

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27 March 2024

https://api.elsevier.com/content/article/PII:S0021925819692665?httpAccept=text/plain

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10.1016/S0021-9258(19)69266-5

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27 March 2024

Journal of Biological Chemistry

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14 October 2019

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14 October 2019

5722-5727

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14 October 2019

11

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Europe PubMed Central

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14 October 2019

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

2

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

3

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NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?

4

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Role of endothelium-derived nitric oxide in the regulation of blood pressure

5

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Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

6

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Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo

7

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NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide

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Inhibition of interleukin-1-alpha-induced nitric oxide synthase in vascular smooth muscle and full reversal of interleukin-1-alpha-induced hypotension by N omega-amino-L-arginine

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Endothelial cell production of nitrogen oxides in response to interferon gamma in combination with tumor necrosis factor, interleukin-1, or endotoxin.

11

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Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages

12

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Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells

13

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Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells

14

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Interleukin-1 beta induces the production of an L-arginine-derived relaxing factor from cultured smooth muscle cells from rat aorta

15

1 reference

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Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase.

18

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Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

20

1 reference

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Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

21

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Localization of nitric oxide synthase indicating a neural role for nitric oxide

22

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Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication

23

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Does endothelium-derived nitric oxide have a role in cytokine-induced hypotension?

24

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Purification of a Ca2+/calmodulin-dependent nitric oxide synthase from porcine cerebellum. Cofactor-role of tetrahydrobiopterin

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Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase

28

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Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin

29

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Guanosine triphosphate cyclohydrolase activity in rat tissues

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Inhibition of GTP cyclohydrolase I by pterins

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Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

32

1 reference

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Neopterin as marker for activation of cellular immunity: immunologic basis and clinical application

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1 reference

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Analysis of reduced forms of biopterin in biological tissues and fluids

36

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Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase.

37

1 reference

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Inhibition of GTP cyclohydrolase I by pterins

38

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Effects of sepiapterin and 6-acetyldihydrohomopterin on the guanosine triphosphate cyclohydrolase I of mouse, rat and the fruit-fly Drosophila

39

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Inhibition of dihydrofolic reductase by aminopterin and amethopterin

40

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Biosynthesis of tetrahydrobiopterin: conversion of dihydroneopterin triphosphate to tetrahydropterin intermediates

41

1 reference

10.1016/S0021-9258(19)69266-5

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Critical Reviews in Immunology

43

9

1

author name string

Dinerello

publication date

1989

1 reference

10.1016/S0021-9258(19)69266-5

https://api.crossref.org/works/10.1016/S0021-9258(19)69266-5

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Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis

45

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Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

46

1 reference

10.1016/S0021-9258(19)69266-5

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Biopterin. III. Purification and characterization of enzymes involved in the cerebral synthesis of 7,8-dihydrobiopterin

47

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Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells

48

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10.1016/S0021-9258(19)69266-5

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Identifiers

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7240168%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

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